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Protein Overview: pyd3-PA

General Information:
Name(s) found: pyd3-PA / FBpp0081276 [FlyBase]
Description(s) found:
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  • gi|23170674|gb|AAF54141.2| pyd3 [Drosophila melanogaster] [NCBI NR]
  • gi|21358471|ref|NP_649732.1| pyd3 [Drosophila melanogaster] [NCBI NR]
  • gi|14334063|gb|AAK60520.1|AF333187_1 beta-alanine synthase [Drosophila melanogaster] [NCBI NR]
  • The gene pyd3 is referred to in FlyBase by the symbol Dmel\pyd3 (CG3027, FBgn0037513). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3573635..3575798. It has the cytological map location 84D14. There is experimental evidence that it has the molecular function</span>: beta-ureidopropionase activity. There is experimental evidence that it is involved in the biological process</span>: 'de novo' pyrimidine base biosynthetic process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG3027-PA translation from_gene[CG3027 pyd3 FBgn0037513] seq_release:3 mol_weight=43800 cds_boundaries:(3R:3,573,760..3,575,723[-]) aa_length:386 transcript_info:[CG3027-RA seq_release:3] gene_info:[gene symbol:pyd3 FBgn0037513 gene_boundaries:(3R:3,5 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VI04) CG3027 protein (Beta-alanine synthase) (EC 3.5.1.6) [DrosMelano7227.FASTAC.txt]
  • CG3027-PA [Drosophila melanogaster]gi|14334063|gb|AAK60520.1| beta-alanine synthase [Drosophila melanogaster]gi|21358471|ref|NP_649732.1| CG3027-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(3573742..3573915,3573976..3574595,3574672..3574934,3575605..3575708); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP [fly-100309-contam.fasta]
  • beta-alanine synthase [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG3027-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • pyd3 CG3027-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(3573742..3573915,3573976..3574595,3574672..3574934,3575605..3575708); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP_649732,GB_protein:AAF54141; MD5=f755d0be74c9326fd13fad9404851ce8; length=386; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(3573742..3573915,3573976..3574595,3574672..3574934,3575605..3575708); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP_649732,GB_protein:AAF54141; MD5=f755d0be74c9326fd13fad9404851ce8; length=386; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Beta-alanine synthase OS=Drosophila melanogaster GN=pyd3 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(3573742..3573915,3573976..3574595,3574672..3574934,3575605..3575708); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP_649732,GB_protein:AAF54141,FlyMine:FBpp0081276,modMine:FBpp0081276; MD5=f755d0be74c9326fd13fad9404851ce8; length=386; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(7749883..7749986,7748950..7749212,7748254..7748873,7748020..7748193)); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP_649732,GB_protein:AAF54141,FlyMine:FBpp0081276,modMine:FBpp0081276; MD5=f755d0be74c9326fd13fad9404851ce8; length=386; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(7749883..7749986,7748950..7749212,7748254..7748873,7748020..7748193)); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP_649732,GB_protein:AAF54141,FlyMine:FBpp0081276,modMine:FBpp0081276; MD5=f755d0be74c9326fd13fad9404851ce8; length=386; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0081276 type=protein; loc=3R:complement(join(7749883..7749986,7748950..7749212,7748254..7748873,7748020..7748193)); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP_649732,GB_protein:AAF54141,FlyMine:FBpp0081276,modMine:FBpp0081276; MD5=f755d0be74c9326fd13fad9404851ce8; length=386; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(7749883..7749986,7748950..7749212,7748254..7748873,7748020..7748193)); ID=FBpp0081276; name=pyd3-PA; parent=FBgn0037513,FBtr0081780; dbxref=FlyBase:FBpp0081276,FlyBase_Annotation_IDs:CG3027-PA,GB_protein:AAF54141.2,REFSEQ:NP_649732,GB_protein:AAF54141,UniProt/TrEMBL:Q9VI04,FlyMine:FBpp0081276,modMine:FBpp0081276; MD5=f755d0be74c9326fd13fad9404851ce8; length=386; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 386 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: pyrimidine base catabolic process [IC]
    'de novo' pyrimidine base biosynthetic process [IGI]
    Molecular Function: beta-ureidopropionase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAFELKNLN DCLEKHLPPD ELKEVKRILY GVEEDQTLEL PTSAKDIAEQ NGFDIKGYRF  60
   61 TAREEQTRKR RIVRVGAIQN SIVIPTTAPI EKQREAIWNK VKTMIKAAAE AGCNIVCTQE 120
  121 AWTMPFAFCT REKFPWCEFA EEAENGPTTK MLAELAKAYN MVIIHSILER DMEHGETIWN 180
  181 TAVVISNSGR YLGKHRKNHI PRVGDFNEST YYMEGNTGHP VFETEFGKLA VNICYGRHHP 240
  241 QNWMMFGLNG AEIVFNPSAT IGRLSEPLWS IEARNAAIAN SYFTVPINRV GTEQFPNEYT 300
  301 SGDGNKAHKE FGPFYGSSYV AAPDGSRTPS LSRDKDGLLV VELDLNLCRQ VKDFWGFRMT 360
  361 QRVPLYAESF KKASEHGFKP QIIKET

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..386] PSI-BLAST 62.522879 hypothetical protein yl85

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • beta-ureidopropionase activity
    		•  2.85740685481813 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  2.08563993959019 bayes_pls_golite062009
  • hydrolase activity
    		•  1.99914043564785 bayes_pls_golite062009
  • catalytic activity
    		•  1.64442398754697 bayes_pls_golite062009
  • N-carbamoylputrescine amidase activity
    		•  0.749539597459006 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle