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Protein Overview: FBpp0304805, CG1...

General Information:
Name(s) found: FBpp0304805 [FlyBase]
CG14606-PA / FBpp0081121 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=3R:complement(3040458..3040655,3040751..3041163,3041227..3041579,3042105..3042235,3042314..3042425,3042485..3042594); ID=FBpp0304805; name=CG14606-PB; parent=FBgn0037485,FBtr0332538; dbxref=FlyBase:FBpp0304805,FlyBase_Annotation_IDs:CG14606-PB,REFSEQ:NP_001262342,GB_protein:AGB95725; MD5=3043771515dd6f8008835850c9693b48; length=438; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG14606 (CG14606, FBgn0037485). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3040061..3042805. It has the cytological map location 84D2. Based on sequence similarity, it is predicted to have molecular function</span>: hexose transmembrane transporter activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 438 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    phagocytosis, engulfment [IMP]
    Molecular Function: hexose transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLTHGIAVG WLSPSLRLLA SDESPLGDPL TITQASWVGS LIGLGSLTGN IIFGLLLDRL  60
   61 GRKVCMYFLA IPNMIYWILI YSAQDVTYLY AGRFLAGMSG GGCYVVLPIF IAEIADNSVR 120
  121 GALSSMAMMY VSIGMMVGFT LASYLPYYLM PCIIVALPVV FMLSVIGLSE TPQYLLRRGR 180
  181 DDQAEKSFYF YKNLTPPTSS DKEASQHDAA KIEFDTFRLQ VLSGGVTESI SWRDFINVPT 240
  241 LKIFGLIFVL IICNQLSGSF AIFNYTSHIF AELGNNLDPN TSTIVVGAAQ LVGIFSAVVL 300
  301 VDRLGRRVLL LTSMGGMGLG ELAIALLKCF ASDEFLNQNG WLPLVIMCLV ACIASLGVIA 360
  361 LIFIIIIELL PAKIRSIGTS LSMATFSGFI FVALKIYPTM IYDQGLAATM FMSAGMCLFG 420
  421 FIVLGLFLPE TKGKLMTH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..438] PSI-BLAST 19.522879 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.20943245291378 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.20943245291378 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.1076219212629 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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