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Protein Overview: Pi4KIIalpha-PB

General Information:
Name(s) found: Pi4KIIalpha-PB / FBpp0078404 [FlyBase]
Description(s) found:
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  • gi|25009772|gb|AAN71059.1| AT12695p [Drosophila melanogaster] [NCBI NR]
  • gi|24644272|ref|NP_730945.1| Pi4KIIalpha, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|23170371|gb|AAN13242.1| Pi4KIIalpha, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene Pi4KIIÃ?&#142;Ã?± is referred to in FlyBase by the symbol Dmel\Pi4KIIÃ?&#142;Ã?± (CG2929, FBgn0037339). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1383385..1389347. It has the cytological map location 83B1-83B2. There is experimental evidence that it has the molecular function</span>: 1-phosphatidylinositol 4-kinase activity. There is experimental evidence that it is involved in the biological process</span>: phosphoinositide phosphorylation. 5 alleles are reported. The phenotype of these alleles is annotated with: rhabdomere. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • >CG2929-PB translation from_gene[CG2929 Pi4KIIalpha FBgn0037339] seq_release:3 mol_weight=63090 cds_boundaries:(3R:1,384,020..1,386,847[-]) aa_length:563 transcript_info:[CG2929-RB seq_release:3] gene_info:[gene symbol:Pi4KIIalpha FBgn0037339 gene_boun [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8I0B7) CG2929-PB (AT12695p) [DrosMelano7227.FASTAC.txt]
  • CG2929-PB, isoform B [Drosophila melanogaster]gi|24644272|ref|NP_730945.1| CG2929-PB [Drosophila melanogaster]gi|25009772|gb|AAN71059.1| AT12695p [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(1384020..1384023,1384089..1384157,1384221..1385041,1385101..1385296,1385394..1385524,1385797..1385915,1386499..1386850); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBas [fly-100309-contam.fasta]
  • CG2929-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Pi4KIIalpha CG2929-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • AT12695p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(1384020..1384023,1384089..1384157,1384221..1385041,1385101..1385296,1385394..1385524,1385797..1385915,1386499..1386850); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBase_Annotation_IDs:CG2929-PB,GB_protein:AAN13242.1,REFSEQ:NP_730945,GB_protein:AAN13242; MD5=b49dc6268b661acbdbad753393e40cae; length=563; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(1384020..1384023,1384089..1384157,1384221..1385041,1385101..1385296,1385394..1385524,1385797..1385915,1386499..1386850); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBase_Annotation_IDs:CG2929-PB,GB_protein:AAN13242.1,REFSEQ:NP_730945,GB_protein:AAN13242; MD5=b49dc6268b661acbdbad753393e40cae; length=563; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • AT12695p OS=Drosophila melanogaster GN=Pi4KIIalpha PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(1384020..1384023,1384089..1384157,1384221..1385041,1385101..1385296,1385394..1385524,1385797..1385915,1386499..1386850); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBase_Annotation_IDs:CG2929-PB,GB_protein:AAN13242.1,REFSEQ:NP_730945,GB_protein:AAN13242,FlyMine:FBpp0078404,modMine:FBpp0078404; MD5=b49dc6268b661acbdbad753393e40cae; length=563; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(5560777..5561128,5560075..5560193,5559672..5559802,5559379..5559574,5558499..5559319,5558367..5558435,5558298..5558301)); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBase_Annotation_IDs:CG2929-PB,GB_protein:AAN13242.1,REFSEQ:NP_730945,GB_protein:AAN13242,FlyMine:FBpp0078404,modMine:FBpp0078404; MD5=b49dc6268b661acbdbad753393e40cae; length=563; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(5560777..5561128,5560075..5560193,5559672..5559802,5559379..5559574,5558499..5559319,5558367..5558435,5558298..5558301)); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBase_Annotation_IDs:CG2929-PB,GB_protein:AAN13242.1,REFSEQ:NP_730945,GB_protein:AAN13242,FlyMine:FBpp0078404,modMine:FBpp0078404; MD5=b49dc6268b661acbdbad753393e40cae; length=563; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VND3, AT12695p OS=Drosophila melanogaster GN=Pi4KIIalpha PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0078404 type=protein; loc=3R:complement(join(5560777..5561128,5560075..5560193,5559672..5559802,5559379..5559574,5558499..5559319,5558367..5558435,5558298..5558301)); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBase_Annotation_IDs:CG2929-PB,GB_protein:AAN13242.1,REFSEQ:NP_730945,GB_protein:AAN13242,FlyMine:FBpp0078404,modMine:FBpp0078404; MD5=b49dc6268b661acbdbad753393e40cae; length=563; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(5560777..5561128,5560075..5560193,5559672..5559802,5559379..5559574,5558499..5559319,5558367..5558435,5558298..5558301)); ID=FBpp0078404; name=Pi4KIIalpha-PB; parent=FBgn0037339,FBtr0078755; dbxref=FlyBase:FBpp0078404,FlyBase_Annotation_IDs:CG2929-PB,GB_protein:AAN13242.1,REFSEQ:NP_730945,GB_protein:AAN13242,UniProt/TrEMBL:Q8I0B7,FlyMine:FBpp0078404,modMine:FBpp0078404; MD5=b49dc6268b661acbdbad753393e40cae; length=563; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 563 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phosphoinositide phosphorylation [IDA]
    Molecular Function: 1-phosphatidylinositol 4-kinase activity [IDA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKNNIKSFL SQVPLPNAIA AKYQEPSEPR DDEQPTTSKD ALESSSSVPS ASAAYACICC  60
   61 EHKCPLEKDF LESQSDKEGD PPFLVNSPSM ARDSKDTVTV QIAAPRCNCA NCPLRNLYDP 120
  121 LFSEIVAKAE GAIENGVLPE RIYQGSSGSY FVKDASHQCL AVFKPKDEEP YGRLNPKWTK 180
  181 WMHKLCCPCC FGRACLIPNQ GYLSESGASL VDRKLNLNVV PKTRVVRLVA ESFNYARIDR 240
  241 QKAKLKKRIK EHYPSAHFNR MSLPLKTGSF QLFVEGYKDA DYWLRRFESE PLPPSVAKSF 300
  301 QLQFERLVVL DYIIRNTDRG NDNWLIKYVA PKITTQVGGT GGRTMHGVVT PKLPNALGAS 360
  361 KIVDLNEPPQ ASPKPTTGGR PSNHLAGGAA TSAQQDSSSL ASSEDEPSSR SPPTSEPDWN 420
  421 VVNSAFIRIA AIDNGLAFPF KHPDSWRAYP YHWAWLPQAK IPFSEEIKEQ VLPQLSDMNF 480
  481 VEEICTELLY LFQQDRGFDK RLFERQMSVM RGQILNLTQA LRDGKSPVQL VQMPAVIVER 540
  541 SSGSRFFSFT QRFQNKSPFF SWC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] deduced N/A No confident structure predictions are available.
    2 View Details [98..233] MSA 3.053964 View MSA. No confident structure predictions are available.
    3 View Details [234..348] MSA 2.055996 View MSA. No confident structure predictions are available.
    4 View Details [349..563] MSA 2.054972 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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