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Protein Overview: hd-PA

General Information:
Name(s) found: hd-PA / FBpp0078445 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene humpty dumpty is referred to in FlyBase by the symbol Dmel\hd (CG2669, FBgn0086695). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1198314..1200353. It has the cytological map location 83A1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: DNA amplification; cell proliferation. 9 alleles are reported. The phenotypes of these alleles are annotated with: chorion; polytene chromosome; follicle cell; imaginal disc; larval brain; endochorion. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 568 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    Biological Process: cell proliferation [IMP]
    S phase of mitotic cell cycle [NAS]
    DNA amplification [IMP]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTEASVASK WTRPDDFIKL QRLKQKKNKL AARVSNNNNR RPRHQVDETD KSKLLEAKLA  60
   61 QKRKNPFAKS TADAKKLRVD PQLADLEPVV TASSCFVRET PTRPAPAKFV LQKYDPQAFA 120
  121 KLFQHPQINA EDEDDAELAA RQKHTAHLPV DWSLKTRARF FCPTELPAIQ LKTSQLASGL 180
  181 TSFVRCMDPQ RTESTLDISD ATRFNQCNYY WQHPHLPWLT LYPRTAKENV GVVVGERERK 240
  241 ALAEEWDFSF RGLFQLLRAR QCPYFYLCAN TFTVLFRAAG VGGRPESHAL VTPSTRGMRQ 300
  301 ALRQEGIEFS MPLKSDNSGN AHDNSFNEES TTTSLGPEAG EDAPPPAQED EDDDEDWLES 360
  361 LGVDERELRR IQSSHARKQQ AAEMREDFSD NSLLLVDGVE CQGFFSYLLN AKSAISTVGR 420
  421 LAGVPPTLLS PVAFPKATMQ HLVPRSKKVR LDGVDYFSID IKGLILPTFL PSVAELLSET 480
  481 RQMFSSTLAS SINTLAFSKA TQKLLETPET PQSDAEGEDA AGQVFGEQNL SECGLLPAVV 540
  541 GSICRTGQHA VGLLERVCYQ RDEGYAWS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] deduced N/A No confident structure predictions are available.
    2 View Details [105..246] MSA 1.021959 View MSA. No confident structure predictions are available.
    3 View Details [247..319] MSA 1.021979 View MSA. No confident structure predictions are available.
    4 View Details [320..433] deduced N/A No confident structure predictions are available.
    5 View Details [434..481] MSA 2.018992 View MSA. No confident structure predictions are available.
    6 View Details [482..568] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle