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Protein Overview: Rpb8-PA

General Information:
Name(s) found: Rpb8-PA / FBpp0078086 [FlyBase]
Description(s) found:
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  • gi|7296484|gb|AAF51770.1| Rpb8 [Drosophila melanogaster] [NCBI NR]
  • gi|21358365|ref|NP_649352.1| Rpb8 [Drosophila melanogaster] [NCBI NR]
  • gi|16768368|gb|AAL28403.1| GM03174p [Drosophila melanogaster] [NCBI NR]
  • The gene Rpb8 is referred to in FlyBase by the symbol Dmel\Rpb8 (CG11246, FBgn0037121). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:21722044..21722801. It has the cytological map location 78E5. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed RNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription from RNA polymerase II promoter. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG11246-PA translation from_gene[CG11246 Rpb8 FBgn0037121] seq_release:3 mol_weight=17204 cds_boundaries:(3L:21,646,471..21,646,917[+]) aa_length:149 transcript_info:[CG11246-RA seq_release:3] gene_info:[gene symbol:Rpb8 FBgn0037121 gene_boundaries:(3 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VNZ3) CG11246 protein (GM03174P) [DrosMelano7227.FASTAC.txt]
  • (AE003595) CG11246 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG11246-PA [Drosophila melanogaster]gi|54642281|gb|EAL31030.1| GA10862-PA [Drosophila pseudoobscura]gi|16768368|gb|AAL28403.1| GM03174p [Drosophila melanogaster]gi|21358365|ref|NP_649352.1| CG11246-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:21722293..21722742; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770; MD5=84766d081cc588f1ff20cd4af6e [fly-100309-contam.fasta]
  • Rpb8 CG11246-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG11246-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GM03174p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:21722293..21722742; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770; MD5=84766d081cc588f1ff20cd4af6e19533; length=149; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:21722293..21722742; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770; MD5=84766d081cc588f1ff20cd4af6e19533; length=149; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GM03174p OS=Drosophila melanogaster GN=Rpb8 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:21722293..21722742; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770,FlyMine:FBpp0078086,modMine:FBpp0078086; MD5=84766d081cc588f1ff20cd4af6e19533; length=149; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:21729193..21729642; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770,FlyMine:FBpp0078086,modMine:FBpp0078086; MD5=84766d081cc588f1ff20cd4af6e19533; length=149; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:21729193..21729642; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770,FlyMine:FBpp0078086,modMine:FBpp0078086; MD5=84766d081cc588f1ff20cd4af6e19533; length=149; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • GM03174p OS=Drosophila melanogaster GN=Rpb8 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0078086 type=protein; loc=3L:21729193..21729642; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770,FlyMine:FBpp0078086,modMine:FBpp0078086; MD5=84766d081cc588f1ff20cd4af6e19533; length=149; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:21729193..21729642; ID=FBpp0078086; name=Rpb8-PA; parent=FBgn0037121,FBtr0078432; dbxref=FlyBase:FBpp0078086,FlyBase_Annotation_IDs:CG11246-PA,GB_protein:AAF51770.1,REFSEQ:NP_649352,GB_protein:AAF51770,UniProt/TrEMBL:Q9VNZ3,FlyMine:FBpp0078086,modMine:FBpp0078086; MD5=84766d081cc588f1ff20cd4af6e19533; length=149; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 149 amino acids

    Gene Ontology:
    Cellular Component: DNA-directed RNA polymerase II, core complex [ISS]
    Biological Process: transcription [IEA]
    transcription from RNA polymerase II promoter [ISS]
    Molecular Function: DNA-directed RNA polymerase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGVLFEDIF NVKDMDPEGK KFDRVSRLHC ESESFKMDLI LDINSWLYPM ELGDKFRLVL  60
   61 ATTLREDGCP DSGEYNPMEH EGTRADSFEY VMYGKIYRIE GDEAHNEASR LSAYVSFGGL 120
  121 LMRLQGDANN LHGFEVDQHM YLLMKRLAF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..149] PSI-BLAST 60.045757 No description for 2f3iA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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