Protein Overview: AP-2-PB

General Information:
Name(s) found:	AP-2-PB / FBpp0078072 [FlyBase]
Description(s) found: Found 24 descriptions. SHOW ALL	The gene AP-2 is referred to in FlyBase by the symbol Dmel\AP-2 (CG7807, FBgn0023417). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:21591958..21606453. It has the cytological map location 78D8-78E1. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; proboscis development; imaginal disc-derived leg morphogenesis; imaginal disc-derived leg joint morphogenesis. 27 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; organ system; mouthpart; nervous system; peripheral nervous system; adult mesothoracic segment; thoracic segment; adult brain; multi-cell-component structure; adult somatic muscle; adult; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	465 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC][IEA]
Biological Process:	imaginal disc-derived leg joint morphogenesis [IMP] imaginal disc-derived leg morphogenesis [IMP] regulation of transcription, DNA-dependent [IEA][ISS] positive regulation of gene-specific transcription from RNA polymerase II promoter [IDA] proboscis development [IMP]
Molecular Function:	transcription factor activity [ISS] RNA polymerase II transcription factor activity [NAS] specific RNA polymerase II transcription factor activity [IDA] sequence-specific DNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHILHRTNDH QFEDQKFMME RLSGHGSLGL SSGSAAYTTH SGGHTGRSGP ATGHSGHSST  60
   61 HGSAATMHHQ SLQSDFQPPY FPPPFHHSTQ SPPQQQNHGA LEYLGTDPYG QPLSSLHHAP 120
  121 LHHYNQLAGL RSTQDQLGIH RTHREAELQG HVTQLSHGFP YTDRRSDYGS AISAGAAHGT 180
  181 RLGHEHESLA LHQALQNAVD DVQAPALDDN VAFMSDLPLI KSMKSGKEAG NIGSGSPSEV 240
  241 FCAVPGRLSL LSSTSKYKVT IAEVQRRLSP PECLNASLLG GVLRRAKSKN GGRLLREKLE 300
  301 KIGLNLPAGR RKAANVTLLT SLVEGEATHL AKDFHFVCET EFPARQLAEY IVRHQTEPQD 360
  361 SYRRKELILH SQQITKELMQ ILSQDRTTHF GTRSQHLLEP SMQRHLTHFS LITHGFGSPA 420
  421 IMAVLHAFQT FLNESLNYLE KLYPSNGGGM VSSSLDKSKI DNEKK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.40

Protein Overview: AP-2-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: