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Protein Overview: Sin-PA

General Information:
Name(s) found: Sin-PA / FBpp0077946 [FlyBase]
Description(s) found:
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  • gi|7296382|gb|AAF51670.1| Sex-lethal interactor [Drosophila melanogaster] [NCBI NR]
  • gi|24667829|ref|NP_524192.2| Sex-lethal interactor [Drosophila melanogaster] [NCBI NR]
  • The gene Sex-lethal interactor is referred to in FlyBase by the symbol Dmel\Sin (CG10582, FBgn0028402). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:21024897..21026661. It has the cytological map location 78A5. There is experimental evidence that it has the molecular function</span>: protein binding. It is reported to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG10582-PA translation from_gene[CG10582 Sin FBgn0028402] seq_release:3 mol_weight=54980 cds_boundaries:(3L:20,949,165..20,950,745[+]) aa_length:486 transcript_info:[CG10582-RA seq_release:3] gene_info:[gene symbol:Sin FBgn0028402 gene_boundaries:(3L: [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VP85) SIN protein [DrosMelano7227.FASTAC.txt]
  • (AE003593) Sin gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG10582-PA [Drosophila melanogaster]gi|24667829|ref|NP_524192.2| CG10582-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(21024989..21025021,21025081..21026151,21026216..21026572); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protei [fly-100309-contam.fasta]
  • CG10582-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Sex-lethal interactor CG10582-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(21024989..21025021,21025081..21026151,21026216..21026572); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protein:AAF51670; MD5=1399e604fda9f8f02f18a6b2abe151db; length=486; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(21024989..21025021,21025081..21026151,21026216..21026572); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protein:AAF51670; MD5=1399e604fda9f8f02f18a6b2abe151db; length=486; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • LD32951p OS=Drosophila melanogaster GN=Sin PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:join(21024989..21025021,21025081..21026151,21026216..21026572); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protein:AAF51670,FlyMine:FBpp0077946,modMine:FBpp0077946; MD5=1399e604fda9f8f02f18a6b2abe151db; length=486; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • LD32951p OS=Drosophila melanogaster GN=Sin PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3L:join(21031889..21031921,21031981..21033051,21033116..21033472); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protein:AAF51670,FlyMine:FBpp0077946,modMine:FBpp0077946; MD5=1399e604fda9f8f02f18a6b2abe151db; length=486; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(21031889..21031921,21031981..21033051,21033116..21033472); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protein:AAF51670,FlyMine:FBpp0077946,modMine:FBpp0077946; MD5=1399e604fda9f8f02f18a6b2abe151db; length=486; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0077946 type=protein; loc=3L:join(21031889..21031921,21031981..21033051,21033116..21033472); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protein:AAF51670,FlyMine:FBpp0077946,modMine:FBpp0077946; MD5=1399e604fda9f8f02f18a6b2abe151db; length=486; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(21031889..21031921,21031981..21033051,21033116..21033472); ID=FBpp0077946; name=Sin-PA; parent=FBgn0028402,FBtr0078288; dbxref=FlyBase:FBpp0077946,FlyBase_Annotation_IDs:CG10582-PA,GB_protein:AAF51670.1,REFSEQ:NP_524192,GB_protein:AAF51670,UniProt/TrEMBL:Q9VP85,FlyMine:FBpp0077946,modMine:FBpp0077946; MD5=1399e604fda9f8f02f18a6b2abe151db; length=486; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 486 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    U1 snRNP [NAS]
    Biological Process: transcription [IEA]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: protein binding [IPI]
    DNA-directed RNA polymerase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDEDDPVVE EIPVFLSKNL RDSLYLFQYP TKTELPNHDD SVIVNCCVKP IAQEVKVDFG  60
   61 LDIESAHFDR FKGEQFAVAA DGKNTYGAVP PKGQERPTYK RGIMDKQAFT SSRSITDVAK 120
  121 YIVGIFTDRE VHLSPLTSIV QMRPVLSHFD KDDKRKKAEL KAQTEDTDDD EVLQQVTVKF 180
  181 ARGNAKNSGK EQRVGTYDSF VQRIADEPWC EAYWHSRGTP TAELERQKLF ATSHHGSSSL 240
  241 ALAPDEYLRK LLPYDEHVQT VAPAAASAAA QVLPVYNKAM LKSMPLLEQL TVLLRDARML 300
  301 SFSDVISILA EHVDPHVAAD KVLALLPQVG ILLHGNWVPK SEVVFPEKVL SHANGVSAEQ 360
  361 MIRARDYILF RFSRTPYLFR AQVMAATQLP PAETLDVLKT VARVNNTKRW ELLLPPDKEF 420
  421 EQKYPELVSR QEYHWTASEQ HYNEMDWARE TKRVRKRSTR KSESQSLTSA MPPPAMNHST 480
  481 TGSVDA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle