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Protein Overview: CG4365-PB

General Information:
Name(s) found: CG4365-PB / FBpp0077910 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4365 (CG4365, FBgn0037024). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20791747..20793181. It has the cytological map location 77E6. Based on sequence similarity, it is predicted to have molecular function</span>: hydroxyacylglutathione hydrolase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 271 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: hydroxyacylglutathione hydrolase activity [ISS]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSTLEDVQL EGMEIKILPA LQDNYMYLIV DTKTREAAVV DPVEPELVIK TVQEQQLTLS  60
   61 KVLTTHHHWD HAGGNEKLLK LWEKELDVYG GDDRIGALNK KVQQDDTFTI GGLHVKCLST 120
  121 PCHTTGHICY HITAQQGSGE GAVFTGDTLF QGGCGRFFEG TPEEMYEALC TKLSALPDAT 180
  181 KVFCGHEYTL QNMSFARHVE PDNEVIQQRI EWAKHRRASQ DPTVPSTIGE EKSWNPFMRV 240
  241 HEATVQKHAG GATDPVVTMG KLRKEKDTFK A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..271] PSI-BLAST 57.522879 Glyoxalase II (hydroxyacylglutathione hydrolase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydroxyacylglutathione hydrolase activity
    		•  3.53012507604564 bayes_pls_golite062009
  • catalytic activity
    		•  0.941400907161877 bayes_pls_golite062009
  • binding
    		•  0.900972948435178 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.802604883362264 bayes_pls_golite062009
  • hydrolase activity
    		•  0.021392930321391 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle