Protein Overview: Six4-PA, Six4-PB

General Information:
Name(s) found:	Six4-PB / FBpp0077933 [FlyBase] Six4-PA / FBpp0077932 [FlyBase]
Description(s) found: Found 40 descriptions. SHOW ALL	The gene Six4 is referred to in FlyBase by the symbol Dmel\Six4 (CG3871, FBgn0027364). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20781986..20785868. It has the cytological map location 77E6. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; gonad development; fat body development; mesoderm development. 9 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: anatomical structure; organ system; organism; embryonic/larval hypodermal muscle; adult; embryo; developing anatomical structure; late extended germ band embryo; germline cell; embryonic somatic muscle; ventral longitudinal muscle; primordium; gonad. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene Six4 is referred to in FlyBase by the symbol Dmel\Six4 (CG3871, FBgn0027364). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20781986..20785868. It has the cytological map location 77E6. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; gonad development; fat body development; mesoderm development. 9 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: anatomical structure; organ system; organism; embryonic/larval hypodermal muscle; adult; embryo; developing anatomical structure; late extended germ band embryo; germline cell; embryonic somatic muscle; ventral longitudinal muscle; primordium; gonad. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	392 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS]
Biological Process:	gonad development [IMP][NAS] myoblast fusion [IMP] mesoderm development [IMP] regulation of transcription, DNA-dependent [IEA] regulation of transcription [IEA][ISS] fat body development [IMP]
Molecular Function:	transcription factor activity [IEA] RNA polymerase II transcription factor activity [ISS][NAS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDKNLDGNN LSVSIGGDLD STSSGGTSSD HSAVHQDNLS SPMAYGSLFL PNAGYRGNLS  60
   61 CKTVLQLDKF APYEGVEKDH LLERRFQDIT NDYDKSPPPT ASTTPTHYPS LNSIIFENGS 120
  121 SGNLGDLNGN TKTDLCAGLQ RSGGGLGGNA GSGGHLISNL TAAHNMSAVS SFPIDAKMLQ 180
  181 FSTDQIQCMC EALQQKGDIE KLTTFLCSLP PSEFFKTNES VLRARAMVAY NLGQFHELYN 240
  241 LLETHCFSIK YHVDLQNLWF KAHYKEAEKV RGRPLGAVDK YRLRKKYPLP KTIWDGEETV 300
  301 YCFKEKSRNA LKDCYLTNRY PTPDEKKTLA KKTGLTLTQV SNWFKNRRQR DRTPQQRPDI 360
  361 MSVLPVGQLD GNGFPRMFNA PSYYPETIFN GQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: Six4-PA, Six4-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: