Protein Overview: kni-PA

General Information:
Name(s) found:	kni-PA / FBpp0077941 [FlyBase]
Description(s) found: Found 25 descriptions. SHOW ALL	The gene knirps is referred to in FlyBase by the symbol Dmel\kni (CG4717, FBgn0001320). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20685430..20688463. It has the cytological map location 77E3. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; ligand-dependent nuclear receptor activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; regulation of mitosis; muscle organ development; epidermis development. 100 alleles are reported. The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: embryonic abdomen; embryonic segment; organ system; embryonic tagma; adult segment; thoracic segment; abdominal segment 7; adult mesothoracic segment; embryonic/larval tracheal system; embryonic abdominal segment 4; extended germ band embryo; embryonic dorsal branch; embryonic/larval hemocoel; embryonic dorsal trunk. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	429 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS][NAS]
Biological Process:	regulation of tube size, open tracheal system [TAS] regulation of mitosis [IMP] epidermis development [IMP] regulation of transcription, DNA-dependent [IEA] trunk segmentation [TAS] zygotic determination of anterior/posterior axis, embryo [NAS][TAS] branched duct epithelial cell fate determination, open tracheal system [TAS] open tracheal system development [TAS] dendrite morphogenesis [IMP] negative regulation of transcription from RNA polymerase II promoter [TAS] muscle organ development [IMP] epithelial cell migration, open tracheal system [TAS] negative regulation of transcription [NAS]
Molecular Function:	transcription factor activity [ISS] zinc ion binding [IEA] ligand-dependent nuclear receptor activity [ISS][NAS] sequence-specific DNA binding [IEA] specific transcriptional repressor activity [NAS][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQTCKVCGE PAAGFHFGAF TCEGCKSFFG RSYNNISTIS ECKNEGKCII DKKNRTTCKA  60
   61 CRLRKCYNVG MSKGGSRYGR RSNWFKIHCL LQEHEQAAAA AGKAPPLAGG VSVGGAPSAS 120
  121 SPVGSPHTPG FGDMAAHLHH HHQQQQQQQV PRHPHMPLLG YPSYLSDPSA ALPFFSMMGG 180
  181 VPHQSPFQLP PHLLFPGYHA SAAAAAASAA DAAYRQEMYK HRQSVDSVES QNRFSPASQP 240
  241 PVVQPTSSAR QSPIDVCLEE DVHSVHSHQS SASLLHPIAI RATPTTPTSS SPLSFAAKMQ 300
  301 SLSPVSVCSI GGETTSVVPV HPPTVSAQEG PMDLSMKTSR SSVHSFNDSG SEDQEVEVAP 360
  361 RRKFYQLEAE CLTTSSSSSS HSAAHSPNTT TAHAEVKRQK LGGAEATHFG GFAVAHNAAS 420
  421 AMRGIFVCV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.70

Protein Overview: kni-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: