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Protein Overview: Clc-PC, Clc-PA, ...

General Information:
Name(s) found: FBpp0305007 [FlyBase]
Clc-PC / FBpp0290348 [FlyBase]
Clc-PB / FBpp0290037 [FlyBase]
Clc-PA / FBpp0074599 [FlyBase]
Description(s) found:
Found 46 descriptions.
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  • type=protein; loc=3L:20235898..20236557; ID=FBpp0305007; name=Clc-PD; parent=FBgn0024814,FBtr0332771; dbxref=REFSEQ:NP_001262101,GB_protein:AGB94794,FlyBase:FBpp0305007,FlyBase_Annotation_IDs:CG6948-PD; MD5=bd747aa55b4cb93542d90ad487ba6d8e; length=219; release=r5.56; species=Dmel; [FlyBase]
  • The gene Clathrin light chain is referred to in FlyBase by the symbol Dmel\Clc (CG6948, FBgn0024814). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20234153..20236835. It has the cytological map location 77A3-77A4. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle coating; neurotransmitter transport; neurotransmitter secretion. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Clathrin light chain is referred to in FlyBase by the symbol Dmel\Clc (CG6948, FBgn0024814). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20234153..20236835. It has the cytological map location 77A3-77A4. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle coating; neurotransmitter transport; neurotransmitter secretion. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Clathrin light chain is referred to in FlyBase by the symbol Dmel\Clc (CG6948, FBgn0024814). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20234153..20236835. It has the cytological map location 77A3-77A4. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle coating; neurotransmitter transport; neurotransmitter secretion. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 219 amino acids

    Gene Ontology:
    Cellular Component: coated pit [ISS][NAS][TAS]
    synaptic vesicle [TAS]
    clathrin coat of trans-Golgi network vesicle [IEA]
    clathrin coat of coated pit [ISS]
    clathrin vesicle coat [ISS][TAS]
    coated vesicle [TAS]
    Biological Process: neurotransmitter transport [ISS]
    synaptic vesicle coating [ISS][TAS]
    intracellular protein transport [IEA]
    neurotransmitter secretion [ISS][NAS]
    Molecular Function: neurotransmitter transporter activity [ISS]
    protein binding [IEA]
    structural molecule activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFGDDFAAK EDVDPAAEFL AREQSALGDL EAEITGGSAS APPAASTDEG LGELLGGTAS  60
   61 EGDLLSAGGT GGLESSTGSF EVIGGESNEP VGISGPPPSR EEPEKIRKWR EEQKQRLEEK 120
  121 DIEEERKKEE LRQQSKKELD DWLRQIGESI SKTKLASRNA EKQAATLENG TIEPGTEWER 180
  181 IAKLCDFNPK VNKAGKDVSR MRSIYLHLKQ NPIQVQKST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A No confident structure predictions are available.
    2 View Details [102..219] PSI-BLAST 8.69897 Clathrin D6 Coat


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle