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Protein Overview: lush-PB, lush-PA

General Information:
Name(s) found: lush-PB / FBpp0290704 [FlyBase]
lush-PA / FBpp0074737 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • The gene lush is referred to in FlyBase by the symbol Dmel\lush (CG8807, FBgn0020277). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19597498..19599190. It has the cytological map location 76B9. There is experimental evidence that it has the molecular function</span>: dibutyl phthalate binding; diphenyl phthalate binding. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; sensory perception of smell; response to pheromone. 5 alleles are reported. The phenotype of these alleles is annotated with: olfactory neuron. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene lush is referred to in FlyBase by the symbol Dmel\lush (CG8807, FBgn0020277). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19597498..19599190. It has the cytological map location 76B9. There is experimental evidence that it has the molecular function</span>: dibutyl phthalate binding; diphenyl phthalate binding. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; sensory perception of smell; response to pheromone. 5 alleles are reported. The phenotype of these alleles is annotated with: olfactory neuron. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 153 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IDA]
    Biological Process: sensory perception of chemical stimulus [UNKNOWN]
    response to ethanol [IDA][TAS]
    sensory perception of smell [IMP][NAS]
    response to pheromone [IDA][IMP]
    olfactory behavior [IMP]
    transport [IEA]
    Molecular Function: dibutyl phthalate binding [IDA]
    [NOT]ethanol binding [IDA]
    odorant binding [UNKNOWN][IEA][NAS][TAS]
    diphenyl phthalate binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHWKRRSSA VFAIVLQVLV LLLPDPAVAM TMEQFLTSLD MIRSGCAPKF KLKTEDLDRL  60
   61 RVGDFNFPPS QDLMCYTKCV SLMAGTVNKK GEFNAPKALA QLPHLVPPEM MEMSRKSVEA 120
  121 CRDTHKQFKE SCERVYQTAK CFSENADGQF MWP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] PSI-BLAST 23.09691 Complex of Drosophila odorant binding protein LUSH with butanol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • odorant binding
    		•  6.54639467875661 bayes_pls_golite062009
  • pheromone binding
    		•  4.60846885062367 bayes_pls_golite062009
  • phenylalkylamine binding
    		•  3.4460817037949 bayes_pls_golite062009
  • binding
    		•  1.84061726818261 bayes_pls_golite062009
  • phthalate binding
    		•  1.4681002768756 bayes_pls_golite062009
  • diphenyl phthalate binding
    		•  1.4681002768756 bayes_pls_golite062009
  • dibutyl phthalate binding
    		•  1.4681002768756 bayes_pls_golite062009
  • ethanol binding
    		•  0.217302871879979 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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