Protein Overview: CG4174-PA

General Information:
Name(s) found:	CG4174-PA / FBpp0074877 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24666334\|ref\|NP_730342.1\| CG4174, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093189\|gb\|AAF49256.2\| CG4174, isoform A [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG4174 (CG4174, FBgn0036793). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18593248..18611031. It has the cytological map location 75D3-75D4. Based on sequence similarity, it is predicted to have molecular function</span>: procollagen-proline 4-dioxygenase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: peptidyl-proline hydroxylation to 4-hydroxy-L-proline. One allele is reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] >CG4174-PA translation from_gene[CG4174 CG4174 FBgn0036793] seq_release:3 mol_weight=50015 cds_boundaries:(3L:18,549,228..18,550,931[-]) aa_length:435 transcript_info:[CG4174-RA seq_release:3] gene_info:[gene symbol:CG4174 FBgn0036793 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] (Q9VVQ4) CG4174 protein [DrosMelano7227.FASTAC.txt] CG4174-PA [Drosophila melanogaster]gi\|24666334\|ref\|NP_730342.1\| CG4174-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18594613..18594789,18594956..18595152); ID=FBpp0074877; name=CG4174-PA; parent=FBgn0036793,FBtr0075111; dbxref=FlyBase_Annotation_IDs:CG4174-PA,Fly [fly-100309-contam.fasta] CG4174-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18594613..18594789,18594956..18595152); ID=FBpp0074877; name=CG4174-PA; parent=FBgn0036793,FBtr0075111; dbxref=FlyBase_Annotation_IDs:CG4174-PA,FlyBase:FBpp0074877,GB_protein:AAF49256.2,REFSEQ:NP_730342,GB_protein:AAF49256; MD5=10fd958af1487d0e7f6b75c4f72c5bcc; length=435; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18594613..18594789,18594956..18595152); ID=FBpp0074877; name=CG4174-PA; parent=FBgn0036793,FBtr0075111; dbxref=FlyBase_Annotation_IDs:CG4174-PA,FlyBase:FBpp0074877,GB_protein:AAF49256.2,REFSEQ:NP_730342,GB_protein:AAF49256; MD5=10fd958af1487d0e7f6b75c4f72c5bcc; length=435; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] CG4174, isoform A OS=Drosophila melanogaster GN=CG4174 PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(18593446..18593468,18593529..18593676,18593739..18594301,18594364..18594563,18594613..18594789,18594956..18595152); ID=FBpp0074877; name=CG4174-PA; parent=FBgn0036793,FBtr0075111; dbxref=FlyBase_Annotation_IDs:CG4174-PA,FlyBase:FBpp0074877,GB_protein:AAF49256.2,REFSEQ:NP_730342,GB_protein:AAF49256,FlyMine:FBpp0074877,modMine:FBpp0074877; MD5=10fd958af1487d0e7f6b75c4f72c5bcc; length=435; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
Organism:	Drosophila melanogaster
Length:	435 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IEA] procollagen-proline 4-dioxygenase complex [IC]
Biological Process:	oxidation reduction [IEA] peptidyl-proline hydroxylation to 4-hydroxy-L-proline [ISS]
Molecular Function:	procollagen-proline 4-dioxygenase activity [ISS] L-ascorbic acid binding [IEA] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA] iron ion binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFHFVVVTA CLGFQVKGEV VSAPESYDFA ISSESQLSLL KLKETHVNNL QSYKKVLKKH  60
   61 LQKIRRLLKK DLGLEQIAVS QMLLTQQPTS VDFEESMGAM HRLQTVYNLD SYAMTEGFID 120
  121 DKDKNIRNWS ADECLMLGLM YLFLKDYNQS ENWLELALYH YDDNVSPEVL KIKLWNYPNL 180
  181 LESLVEANKG LGHYFEAKKY ANELLSINPN HTYMLTQLPK LKHLQSNPAK LTKPKKVFQL 240
  241 QKEICSKRYR RKSGVLVCRY VDWTPFLKLA PLKMEELSMK PYISIFYGFL GQKDIEVLKN 300
  301 VSRPKLQRIE HLSGNCSCKI GNLSTSLHDV VRKVNELILG ITGFPLKGNQ MLEVINYGIA 360
  361 GNYNPEEPKI HNKANAFIFL SNAGKGGEIV FPSRHLKVRP RKGSMLVWEN LKKSLIYHQC 420
  421 PILKGNMWVA NKVLN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CG4174-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: