Protein Overview: Exn-PA, Exn-PC, ...

General Information:
Name(s) found:	Exn-PA / FBpp0291789 [FlyBase] Exn-PC / FBpp0291788 [FlyBase] Exn-PB / FBpp0291787 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7294030\|gb\|AAF49386.1\| ephexin, isoform A [Drosophila melanogaster] [NCBI NR] gi\|5052528\|gb\|AAD38594.1\|AF145619_1 BcDNA.GH03693 [Drosophila melanogaster] [NCBI NR] gi\|24665696\|ref\|NP_730229.1\| ephexin, isoform C [Drosophila melanogaster] [NCBI NR] gi\|24665692\|ref\|NP_730228.1\| ephexin, isoform B [Drosophila melanogaster] [NCBI NR] gi\|23093285\|gb\|AAN11725.1\| ephexin, isoform C [Drosophila melanogaster] [NCBI NR] gi\|23093284\|gb\|AAN11724.1\| ephexin, isoform B [Drosophila melanogaster] [NCBI NR] gi\|21355583\|ref\|NP_648942.1\| ephexin, isoform A [Drosophila melanogaster] [NCBI NR] gi\|133753042\|gb\|ABO38128.1\| Ephexin [Drosophila melanogaster] [NCBI NR] The gene Ephexin is referred to in FlyBase by the symbol Dmel\Exn (CG42665, FBgn0261547). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16963517..16987501. It has the cytological map location 73E1-73E2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: Rho guanyl-nucleotide exchange factor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of neurotransmitter secretion. 20 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] >CG3799-PB translation from_gene[CG3799 BcDNA:GH03693 FBgn0027593] seq_release:3 mol_weight=117302 cds_boundaries:(3L:16,939,408..16,943,018[+]) aa_length:1051 transcript_info:[CG3799-RB seq_release:3] gene_info:[gene symbol:BcDNA:GH03693 FBgn0027593 g [hmr_yeast5_DM3-1_pombe.fasta] >CG3799-PC translation from_gene[CG3799 BcDNA:GH03693 FBgn0027593] seq_release:3 mol_weight=117302 cds_boundaries:(3L:16,939,408..16,943,018[+]) aa_length:1051 transcript_info:[CG3799-RC seq_release:3] gene_info:[gene symbol:BcDNA:GH03693 FBgn0027593 g [hmr_yeast5_DM3-1_pombe.fasta] >CG3799-PA translation from_gene[CG3799 BcDNA:GH03693 FBgn0027593] seq_release:3 mol_weight=117302 cds_boundaries:(3L:16,939,408..16,943,018[+]) aa_length:1051 transcript_info:[CG3799-RA seq_release:3] gene_info:[gene symbol:BcDNA:GH03693 FBgn0027593 g [hmr_yeast5_DM3-1_pombe.fasta] (Q9Y150) BCDNA:GH03693 protein [DrosMelano7227.FASTAC.txt] (AE003525) BcDNA:GH03693 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG3799-PC, isoform C [Drosophila melanogaster]gi\|23093284\|gb\|AAN11724.1\| CG3799-PB, isoform B [Drosophila melanogaster]gi\|7294030\|gb\|AAF49386.1\| CG3799-PA, isoform A [Drosophila melanogaster]gi\|24665696\|ref\|NP_730229.1\| CG3799-PC [Drosophila melanogast [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075031; name=Exn-PB; parent=FBgn0027593,FBtr0075271; dbxref=FlyBase:FBpp0075031,FlyBas [fly-100309-contam.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075032; name=Exn-PC; parent=FBgn0027593,FBtr0075272; dbxref=FlyBase:FBpp0075032,FlyBas [fly-100309-contam.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075033; name=Exn-PA; parent=FBgn0027593,FBtr0075273; dbxref=FlyBase:FBpp0075033,FlyBas [fly-100309-contam.fasta] BcDNA.GH03693 [Drosophila melanogaster] [nr-271106-contam.fasta] CG3799-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] CG3799-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG3799-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075031; name=Exn-PB; parent=FBgn0027593,FBtr0075271; dbxref=FlyBase:FBpp0075031,FlyBase_Annotation_IDs:CG3799-PB,GB_protein:AAN11724.1,REFSEQ:NP_730228,GB_protein:AAN11724; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075032; name=Exn-PC; parent=FBgn0027593,FBtr0075272; dbxref=FlyBase:FBpp0075032,FlyBase_Annotation_IDs:CG3799-PC,GB_protein:AAN11725.1,REFSEQ:NP_730229,GB_protein:AAN11725; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075033; name=Exn-PA; parent=FBgn0027593,FBtr0075273; dbxref=FlyBase:FBpp0075033,FlyBase_Annotation_IDs:CG3799-PA,GB_protein:AAF49386.1,REFSEQ:NP_648942,GB_protein:AAF49386; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075031; name=Exn-PB; parent=FBgn0027593,FBtr0075271; dbxref=FlyBase:FBpp0075031,FlyBase_Annotation_IDs:CG3799-PB,GB_protein:AAN11724.1,REFSEQ:NP_730228,GB_protein:AAN11724; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075032; name=Exn-PC; parent=FBgn0027593,FBtr0075272; dbxref=FlyBase:FBpp0075032,FlyBase_Annotation_IDs:CG3799-PC,GB_protein:AAN11725.1,REFSEQ:NP_730229,GB_protein:AAN11725; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0075033; name=Exn-PA; parent=FBgn0027593,FBtr0075273; dbxref=FlyBase:FBpp0075033,FlyBase_Annotation_IDs:CG3799-PA,GB_protein:AAF49386.1,REFSEQ:NP_648942,GB_protein:AAF49386; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] BcDNA.GH03693 OS=Drosophila melanogaster GN=Exn PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0291787; name=Exn-PB; parent=FBgn0261547,FBtr0302647; dbxref=FlyBase_Annotation_IDs:CG42665-PB,FlyBase_Annotation_IDs:CG3799-PB,FlyBase:FBpp0075031,FlyBase:FBpp0291787,REFSEQ:NP_730228,GB_protein:AAN11724; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0291788; name=Exn-PC; parent=FBgn0261547,FBtr0302648; dbxref=FlyBase_Annotation_IDs:CG42665-PC,FlyBase_Annotation_IDs:CG3799-PC,FlyBase:FBpp0075032,FlyBase:FBpp0291788,REFSEQ:NP_730229,GB_protein:AAN11725,FlyMine:FBpp0291788,modMine:FBpp0291788; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(16983628..16983979,16984114..16984361,16984424..16985398,16985460..16985649,16985717..16986738,16986809..16987013,16987078..16987241); ID=FBpp0291789; name=Exn-PA; parent=FBgn0261547,FBtr0302649; dbxref=FlyBase_Annotation_IDs:CG42665-PA,FlyBase_Annotation_IDs:CG3799-PA,FlyBase:FBpp0075033,FlyBase:FBpp0291789,REFSEQ:NP_648942,GB_protein:AAF49386; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291787; name=Exn-PB; parent=FBgn0261547,FBtr0302647; dbxref=FlyBase_Annotation_IDs:CG42665-PB,FlyBase_Annotation_IDs:CG3799-PB,FlyBase:FBpp0075031,FlyBase:FBpp0291787,REFSEQ:NP_730228,GB_protein:AAN11724; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291788; name=Exn-PC; parent=FBgn0261547,FBtr0302648; dbxref=FlyBase_Annotation_IDs:CG42665-PC,FlyBase_Annotation_IDs:CG3799-PC,FlyBase:FBpp0075032,FlyBase:FBpp0291788,REFSEQ:NP_730229,GB_protein:AAN11725,FlyMine:FBpp0291788,modMine:FBpp0291788; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291789; name=Exn-PA; parent=FBgn0261547,FBtr0302649; dbxref=FlyBase_Annotation_IDs:CG42665-PA,FlyBase_Annotation_IDs:CG3799-PA,FlyBase:FBpp0075033,FlyBase:FBpp0291789,REFSEQ:NP_648942,GB_protein:AAF49386; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291787; name=Exn-PB; parent=FBgn0261547,FBtr0302647; dbxref=FlyBase_Annotation_IDs:CG42665-PB,FlyBase_Annotation_IDs:CG3799-PB,FlyBase:FBpp0075031,FlyBase:FBpp0291787,REFSEQ:NP_730228,GB_protein:AAN11724; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291788; name=Exn-PC; parent=FBgn0261547,FBtr0302648; dbxref=FlyBase_Annotation_IDs:CG42665-PC,FlyBase_Annotation_IDs:CG3799-PC,FlyBase:FBpp0075032,FlyBase:FBpp0291788,REFSEQ:NP_730229,GB_protein:AAN11725,FlyMine:FBpp0291788,modMine:FBpp0291788; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291789; name=Exn-PA; parent=FBgn0261547,FBtr0302649; dbxref=FlyBase_Annotation_IDs:CG42665-PA,FlyBase_Annotation_IDs:CG3799-PA,FlyBase:FBpp0075033,FlyBase:FBpp0291789,REFSEQ:NP_648942,GB_protein:AAF49386; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9VVC6, BcDNA.GH03693 OS=Drosophila melanogaster GN=Exn PE=2 SV=1 [DROME.fasta.20160308] FBpp0291787 type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291787; name=Exn-PB; parent=FBgn0261547,FBtr0302647; dbxref=FlyBase_Annotation_IDs:CG42665-PB,FlyBase_Annotation_IDs:CG3799-PB,FlyBase:FBpp0075031,FlyBase:FBpp0291787,REFSEQ:NP_730228,GB_protein:AAN11724; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0291788 type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291788; name=Exn-PC; parent=FBgn0261547,FBtr0302648; dbxref=FlyBase_Annotation_IDs:CG42665-PC,FlyBase_Annotation_IDs:CG3799-PC,FlyBase:FBpp0075032,FlyBase:FBpp0291788,REFSEQ:NP_730229,GB_protein:AAN11725,FlyMine:FBpp0291788,modMine:FBpp0291788; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0291789 type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291789; name=Exn-PA; parent=FBgn0261547,FBtr0302649; dbxref=FlyBase_Annotation_IDs:CG42665-PA,FlyBase_Annotation_IDs:CG3799-PA,FlyBase:FBpp0075033,FlyBase:FBpp0291789,REFSEQ:NP_648942,GB_protein:AAF49386; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291787; name=Exn-PB; parent=FBgn0261547,FBtr0302647; dbxref=FlyBase_Annotation_IDs:CG42665-PB,FlyBase_Annotation_IDs:CG3799-PB,FlyBase:FBpp0075031,FlyBase:FBpp0291787,REFSEQ:NP_730228,GB_protein:AAN11724,UniProt/TrEMBL:Q9Y150; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291788; name=Exn-PC; parent=FBgn0261547,FBtr0302648; dbxref=FlyBase_Annotation_IDs:CG42665-PC,FlyBase_Annotation_IDs:CG3799-PC,FlyBase:FBpp0075032,FlyBase:FBpp0291788,REFSEQ:NP_730229,GB_protein:AAN11725,UniProt/TrEMBL:Q9Y150,FlyMine:FBpp0291788,modMine:FBpp0291788; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:join(16990528..16990879,16991014..16991261,16991324..16992298,16992360..16992549,16992617..16993638,16993709..16993913,16993978..16994141); ID=FBpp0291789; name=Exn-PA; parent=FBgn0261547,FBtr0302649; dbxref=FlyBase_Annotation_IDs:CG42665-PA,FlyBase_Annotation_IDs:CG3799-PA,FlyBase:FBpp0075033,FlyBase:FBpp0291789,REFSEQ:NP_648942,GB_protein:AAF49386,UniProt/TrEMBL:Q9Y150; MD5=587f349e160c7a6662e5ca37da5a8a3c; length=1051; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1051 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [IDA] neuromuscular junction [IDA] U2 snRNP [ISS] small nuclear ribonucleoprotein complex [ISS]
Biological Process:	regulation of Rho protein signal transduction [IEA] regulation of neurotransmitter secretion [IGI]
Molecular Function:	Rho guanyl-nucleotide exchange factor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSALNRSNGQ RLSCSGSLSS SGHPADPVTL PRKRRPRARG EVGVTCQGSS TVYLNGPVSA  60
   61 EPIRPAPEPI YQNEAAAISQ RCSYSHQRAQ LLTSMRVTVA EGAENDAKVT MEVSTFVDDS 120
  121 DHYYETLSPL GNKRHSTQLV RQSQDGNRSG GVRSSHRRSK NHSASAHTLG EHVVISDDYD 180
  181 SFETDSDDHG DGEPDLRQRN YNDSGVDMRN HRLPKPPPPQ NQVYEFVRKF KDFISSKKSP 240
  241 KGSQQKLYEN TPASTLFYVE CSKRTEDVYE NTDFGPERIP APETKGPVHQ EQAPVLRAKQ 300
  301 KNGKSLRSRL RKSLVGSSFD TKQLSSLAPT RSTFYVEDPE GSLPALPLEP EIHGSGELDS 360
  361 GFSDKNCTPL PETPKFSTVA RKAKKEAKAN RRRTTIGLRP NDPPPPPPPM TGNKSPLDPE 420
  421 RELDAEQTTS WYAECGVFKQ ATNGAVSPRG DEPVTPTPSG HGGVSSWYAE SGLYQTSGIS 480
  481 VASSSGSSGV STGNEAGLGD ELSSEPHSLF SNEPLYQMYS AAKLESITRD LEAHGSSDGY 540
  541 EEIGLQAKAK PEPLVKPRPT ALQLVEPKNG PSRTLWSEIP EVIHSCILPT LTSRERSLQE 600
  601 AKFEIITSEA SYLKSLNLLR RHFMNHNAFL DSSVLSAKDR KALFSYIVPV HECSERLLTE 660
  661 LEACWQDNIM LLGLSRCIYE IAERHFHVYV AFCEHQGRMD RTLRRLKESK ESLAFQQHLE 720
  721 RLEASPSCCG LNLHSFLMLP MQRITRLPLL IDAVFSKESP LNREEYESWK LTLALVQKVV 780
  781 GQCNEAANRW EQAFELERIA RQLEFPSHVR ALAIAPVGVP RAGAKPRFLV KRGELTHLLW 840
  841 RGEDAKLTFG KRLTKISIYA FLFSDLLLLC KRRGESCFSV FDYCPRSMLT LAAGDSLPQL 900
  901 PTKDLKDQAG KNLILMTLLE NCDRKTVELV LSCPSVSDQQ RWLQAMRPPE AETPGEKLYE 960
  961 SWDCPQVVAK HSYESDEPDV LQLELGDVVN VSRKLPDGWY QGERIRDGAV GWFPGSYTEE1020
 1021 LNSAHVRARN LKQRHRLLTF TATYLESQKS K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Exn-PA, Exn-PC, ...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: