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Protein Overview: FBpp0303379

General Information:
Name(s) found: FBpp0303379 [FlyBase]
Description(s) found:
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  • gi|28574919|ref|NP_524059.4| bruno-3, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|23093533|gb|AAF49799.2| bruno-3, isoform B [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=3L:complement(13531844..13531971,13532043..13532219,13533664..13533741,13534589..13534687,13534822..13535098,13535175..13535318,13577292..13577371,13631617..13631665,13657519..13657578); ID=FBpp0303379; name=bru-3-PB; parent=FBgn0264001,FBtr0330347; dbxref=FlyBase:FBpp0303379,FlyBase_Annotation_IDs:CG43744-PB,REFSEQ:NP_524059,GB_protein:AAF49799; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r5.56; species=Dmel; [FlyBase]
  • The gene bruno-3 is referred to in FlyBase by the symbol Dmel\bru-3 (CG12478, FBgn0036379). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:13531018..13659849. It has the cytological map location 70B5-70C2. There is experimental evidence that it has the molecular function</span>: RNA binding; protein homodimerization activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of translation. 14 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG12478-PB translation from_gene[CG12478 bru-3 FBgn0036379] seq_release:3 mol_weight=38452 cds_boundaries:(3L:13,496,315..13,622,046[-]) aa_length:363 transcript_info:[CG12478-RB seq_release:3] gene_info:[gene symbol:bru-3 synonyms:[CG10046] FBgn00363 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VU90) CG12478 protein [DrosMelano7227.FASTAC.txt]
  • CG12478-PB, isoform B [Drosophila melanogaster]gi|28574919|ref|NP_524059.4| CG12478-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:complement(13531844..13531971,13532043..13532219,13533664..13533741,13534589..13534687,13534822..13535098,13535175..13535318,13577292..13577371,13631617..13631665,13657519..13657578); ID=FBpp0075558; name=bru-3-PB; parent=FBgn0036379, [fly-100309-contam.fasta]
  • CG12478-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • bruno-3 CG12478-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:complement(13531844..13531971,13532043..13532219,13533664..13533741,13534589..13534687,13534822..13535098,13535175..13535318,13577292..13577371,13631617..13631665,13657519..13657578); ID=FBpp0075558; name=bru-3-PB; parent=FBgn0036379,FBtr0075816; dbxref=FlyBase:FBpp0075558,FlyBase_Annotation_IDs:CG12478-PB,GB_protein:AAF49799.2,REFSEQ:NP_524059,GB_protein:AAF49799; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:complement(13531844..13531971,13532043..13532219,13533664..13533741,13534589..13534687,13534822..13535098,13535175..13535318,13577292..13577371,13631617..13631665,13657519..13657578); ID=FBpp0075558; name=bru-3-PB; parent=FBgn0036379,FBtr0075816; dbxref=FlyBase:FBpp0075558,FlyBase_Annotation_IDs:CG12478-PB,GB_protein:AAF49799.2,REFSEQ:NP_524059,GB_protein:AAF49799; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Bruno-3, isoform B OS=Drosophila melanogaster GN=bru-3 PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:complement(13531844..13531971,13532043..13532219,13533664..13533741,13534589..13534687,13534822..13535098,13535175..13535318,13577292..13577371,13631617..13631665,13657519..13657578); ID=FBpp0303379; name=bru-3-PB; parent=FBgn0264001,FBtr0330347; dbxref=FlyBase:FBpp0303379,FlyBase_Annotation_IDs:CG43744-PB; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:complement(join(13664419..13664478,13638517..13638565,13584192..13584271,13542075..13542218,13541722..13541998,13541489..13541587,13540564..13540641,13538943..13539119,13538744..13538871)); ID=FBpp0303379; name=bru-3-PB; parent=FBgn0264001,FBtr0330347; dbxref=FlyBase:FBpp0303379,FlyBase_Annotation_IDs:CG43744-PB,REFSEQ:NP_524059,GB_protein:AAF49799; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:complement(join(13664419..13664478,13638517..13638565,13584192..13584271,13542075..13542218,13541722..13541998,13541489..13541587,13540564..13540641,13538943..13539119,13538744..13538871)); ID=FBpp0303379; name=bru-3-PB; parent=FBgn0264001,FBtr0330347; dbxref=FlyBase:FBpp0303379,FlyBase_Annotation_IDs:CG43744-PB,REFSEQ:NP_524059,GB_protein:AAF49799; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VU91, Bruno-3, isoform B OS=Drosophila melanogaster GN=bru-3 PE=4 SV=2 [DROME.fasta.20160308]
  • FBpp0303379 type=protein; loc=3L:complement(join(13664419..13664478,13638517..13638565,13584192..13584271,13542075..13542218,13541722..13541998,13541489..13541587,13540564..13540641,13538943..13539119,13538744..13538871)); ID=FBpp0303379; name=bru-3-PB; parent=FBgn0264001,FBtr0330347; dbxref=FlyBase:FBpp0303379,FlyBase_Annotation_IDs:CG43744-PB,REFSEQ:NP_524059,GB_protein:AAF49799; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:complement(join(13664419..13664478,13638517..13638565,13584192..13584271,13542075..13542218,13541722..13541998,13541489..13541587,13540564..13540641,13538943..13539119,13538744..13538871)); ID=FBpp0303379; name=bru3-PB; parent=FBgn0264001,FBtr0330347; dbxref=FlyBase:FBpp0303379,FlyBase_Annotation_IDs:CG43744-PB,REFSEQ:NP_524059,GB_protein:AAF49799,UniProt/TrEMBL:Q9VU90; MD5=f86fd47ab73124aefb8e097b63af5204; length=363; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 363 amino acids

    Gene Ontology:
    Cellular Component: protein complex [IDA]
    Biological Process: negative regulation of translation [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    protein homodimerization activity [IDA]
    RNA binding [IDA]
    mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVHIIELVGQ PKVEFAQQVT MNRALQLKPA ENESRSGCAF VKFGSQQEAQ SAITNLHGSQ  60
   61 TMPGASSSLV VKYADTEKER QIRRMQQMAG HMNLLNPFVF NQFSPYGAYA QQQQQAALMA 120
  121 AAATAPGSAA AYMNPMAALA TQIPHGLNGT GQPPSLPSPT MPNFNMGANT PNGQPGGAAA 180
  181 AAAAAAAADG VFTNGIPQTA FPGHPLHLTI PPQGLPNGDA ATLQHAFPGL PPFPGVAFPA 240
  241 VYGQFPQALP PPLAAVAPTQ REDFLMFPGC SISGPEGCNL FIYHLPQEFG DAELMQMFLP 300
  301 FGNVISSKVF IDRATNQSKC FGFVSFDNPA SAQAAIQAMN GFQIGMKRLK VQLKRPKDAS 360
  361 RPY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle