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Protein Overview: FBpp0304386, Syx...

General Information:
Name(s) found: FBpp0304386 [FlyBase]
Syx13-PA / FBpp0075620 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=3L:join(13038020..13038695,13039317..13039495); ID=FBpp0304386; name=Syx13-PB; parent=FBgn0036341,FBtr0332076; dbxref=FlyBase:FBpp0304386,FlyBase_Annotation_IDs:CG11278-PB,REFSEQ:NP_001261794,GB_protein:AGB94487; MD5=5d83c4b62c35a780e2b59fb42c043ea9; length=284; release=r5.56; species=Dmel; [FlyBase]
  • The gene Syntaxin 13 is referred to in FlyBase by the symbol Dmel\Syx13 (CG11278, FBgn0036341). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:13037536..13040001. It has the cytological map location 69F6. Based on sequence similarity, it is predicted to have molecular function</span>: SNAP receptor activity. There is experimental evidence that it is involved in the biological process</span>: cytokinesis after mitosis; female meiosis; mitosis; male meiosis; cytokinesis after meiosis I. 5 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; anatomical structure; female germline cyst; cell cycle; germline cell; gamete; polytene chromosome chromocenter; spermatozoon; peripheral nervous system; karyosome. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 284 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISS]
    Biological Process: synaptic vesicle docking during exocytosis [ISS]
    vesicle-mediated transport [ISS]
    female meiosis [IMP]
    cytokinesis after meiosis I [IMP]
    male meiosis [IMP]
    cytokinesis after mitosis [IMP]
    mitosis [IMP]
    intracellular protein transport [IEA]
    neurotransmitter secretion [ISS]
    Molecular Function: SNAP receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKALNNPGG NGGGGGPHRD YGAMADSTPE VSFAAAGGSS GFSPTEFMSL SEDIGHNITA  60
   61 IHSSTKQLEK QLKLIGTSKE QPNLREKVHT INTKCNARVQ TTSQDLQRLQ AVVRHGDRQQ 120
  121 KLQLEKLTRE FHGVVEKYSN LQRRISSAMR QTLQQAQQFA DQVVETNARA ELLQQQRLEQ 180
  181 AHLQQEHDML DDRRRQVEQI ESDIIDVNQI MTQLSGLVHD QGQQMDFIEN SIEQTAANVE 240
  241 DGTSELAKAA RSRQSYRRKI LILLVIAVII GLIVTGVIVA KLNS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..284] PSI-BLAST 25.30103 Syntaxin 1A N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • SNAP receptor activity
    		•  3.50393203740159 bayes_pls_golite062009
  • binding
    		•  2.90318399946307 bayes_pls_golite062009
  • SNARE binding
    		•  1.85060343142976 bayes_pls_golite062009
  • transporter activity
    		•  1.74189664015129 bayes_pls_golite062009
  • protein binding
    		•  1.51700626946713 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.49085442233849 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.13101548288086 bayes_pls_golite062009
  • protein transporter activity
    		•  1.09007120264887 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.643064875848901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.370484918396857 bayes_pls_golite062009
  • extracellular ligand-gated ion channel activity
    		•  0.27873535382283 bayes_pls_golite062009
  • excitatory extracellular ligand-gated ion channel activity
    		•  0.27873535382283 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0172309833091902 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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