Protein Overview: wls-PA

General Information:
Name(s) found:	wls-PA / FBpp0075947 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|88911314\|gb\|ABD58936.1\| wntless isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093689\|gb\|AAF50085.2\| wntless, isoform A [Drosophila melanogaster] [NCBI NR] gi\|21356495\|ref\|NP_648445.1\| wntless, isoform A [Drosophila melanogaster] [NCBI NR] gi\|16767860\|gb\|AAL28148.1\| GH01813p [Drosophila melanogaster] [NCBI NR] Protein wntless OS=Drosophila melanogaster GN=wls PE=1 SV=1 [Swiss-Prot] The gene wntless is referred to in FlyBase by the symbol Dmel\wls (CG6210, FBgn0036141). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11159720..11162741. It has the cytological map location 68A9. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: peptide secretion; imaginal disc-derived wing margin morphogenesis; cuticle pattern formation; imaginal disc-derived wing morphogenesis; Wnt receptor signaling pathway; imaginal disc-derived leg morphogenesis; segment polarity determination; compound eye morphogenesis. 19 alleles are reported. The phenotypes of these alleles are annotated with: leg; eye; ovary; wing margin bristle; testis; adult antennal segment; mesothoracic tergum; wing; arista. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG6210-PA translation from_gene[CG6210 CG6210 FBgn0036141] seq_release:3 mol_weight=67891 cds_boundaries:(3L:11,124,764..11,126,977[-]) aa_length:594 transcript_info:[CG6210-RA seq_release:3] gene_info:[gene symbol:CG6210 FBgn0036141 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] (Q95ST2) GH01813p (CG6210-PA) [DrosMelano7227.FASTAC.txt] CG6210-PA, isoform A [Drosophila melanogaster]gi\|16767860\|gb\|AAL28148.1\| GH01813p [Drosophila melanogaster]gi\|21356495\|ref\|NP_648445.1\| CG6210-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(11160329..11160708,11160919..11161014,11161237..11162545); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_p [fly-100309-contam.fasta] CG6210-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] wntless isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] GH01813p [Drosophila melanogaster] [nr-271106-contam.fasta] sprinter CG6210-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(11160329..11160708,11160919..11161014,11161237..11162545); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_protein:AAF50085; MD5=120d5b23dde07be41e966335ab4865aa; length=594; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(11160329..11160708,11160919..11161014,11161237..11162545); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_protein:AAF50085; MD5=120d5b23dde07be41e966335ab4865aa; length=594; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(11160329..11160708,11160919..11161014,11161237..11162545); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_protein:AAF50085,FlyMine:FBpp0075947,modMine:FBpp0075947; MD5=120d5b23dde07be41e966335ab4865aa; length=594; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(join(11168137..11169445,11167819..11167914,11167229..11167608)); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_protein:AAF50085,FlyMine:FBpp0075947,modMine:FBpp0075947; MD5=120d5b23dde07be41e966335ab4865aa; length=594; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(11168137..11169445,11167819..11167914,11167229..11167608)); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_protein:AAF50085,FlyMine:FBpp0075947,modMine:FBpp0075947; MD5=120d5b23dde07be41e966335ab4865aa; length=594; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0075947 type=protein; loc=3L:complement(join(11168137..11169445,11167819..11167914,11167229..11167608)); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_protein:AAF50085,FlyMine:FBpp0075947,modMine:FBpp0075947; MD5=120d5b23dde07be41e966335ab4865aa; length=594; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(11168137..11169445,11167819..11167914,11167229..11167608)); ID=FBpp0075947; name=wls-PA; parent=FBgn0036141,FBtr0076218; dbxref=FlyBase:FBpp0075947,FlyBase_Annotation_IDs:CG6210-PA,GB_protein:AAF50085.2,REFSEQ:NP_648445,GB_protein:AAF50085,UniProt/Swiss-Prot:Q95ST2,FlyMine:FBpp0075947,modMine:FBpp0075947; MD5=120d5b23dde07be41e966335ab4865aa; length=594; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	594 amino acids
Gene Ontology:
Cellular Component:	Golgi apparatus [IDA] plasma membrane [IDA]
Biological Process:	imaginal disc-derived leg morphogenesis [IMP] compound eye morphogenesis [IMP] imaginal disc-derived wing morphogenesis [IMP] segment polarity determination [IMP] Wnt receptor signaling pathway [IMP] imaginal disc-derived wing margin morphogenesis [IMP] peptide secretion [IMP] cuticle pattern formation [IMP]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGTILENLS GRKLSILVAT LLLCQVLCFL LGGLYAPLPA GHVTVLGSLC REDHARQNDT  60
   61 SFLLYSRGAG ACIPVTREEV EQDSTKMANE LVHVFQMPLP RDLRDLDYSR WQQNLIGVLQ 120
  121 VEFGYDSSSE LREPPRELQL TIDMRLAYRN KGDPDNGWKL YAHGVEHRYL DCVTSHVGPT 180
  181 ETLYSCDMIP LFELGALHHS FYLLNLRFPL DTPSQMNLQF GHMHDLTLTA IHQNGGFTQI 240
  241 WLLLKTMLFP FVVGIMIWFW RRVHLLQRSP ALLEYMLIYL GAALTFLNLP LEYLSLVYEM 300
  301 PYMLLLSDIR QGIFYAMLLT FWLVFAGEHM LIQDAPNKST IRSRYWKHLS AVVVGCISLF 360
  361 VFDICERGVQ LRNPFYSIWT TPLGAKVAMT FIVLAGVSAA IYFLFLCYMI WKVFRNIGDK 420
  421 RTSLPSMSQA RRLHYEVPLD QKVEDWAGIV YFYTKAFFFQ LHKANESKGL IYRFKFLMLA 480
  481 TLVCAALTVA GFIMGQMAEG QWDWNDNVAI QPTSAFLTGV YGMWNIYIFA LLILYAPSHK 540
  541 QWPTMHHSDE TTQSNENIVA SAASEEIEFS HLPSDSNPSE ISSLTSFTRK VAFD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: wls-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: