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Protein Overview: CG6673-PA

General Information:
Name(s) found: CG6673-PA / FBpp0076378 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6673 (CG6673, FBgn0035906). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8514539..8516600. It has the cytological map location 66D5. There is experimental evidence that it has the molecular function</span>: glutathione dehydrogenase (ascorbate) activity; transferase activity, transferring sulfur-containing groups. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; response to oxidative stress. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 251 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: response to oxidative stress [IMP]
    determination of adult lifespan [IMP]
    metabolic process [IEA]
    Molecular Function: glutathione dehydrogenase (ascorbate) activity [IDA][NAS]
    [NOT]pyrimidodiazepine synthase activity [IDA]
    glutathione transferase activity [ISS][NAS]
    transferase activity, transferring sulfur-containing groups [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALPQKHFKR GSTKPELPED GVPRFFSMAF CPFSHRVRLM LAAKHIEHHK IYVDLIEKPE  60
   61 WYKDFSPLGK VPALQLTGVK DQPTLVESLI IAEYLDQQYP QTRLFPTDPL QKALDKILIE 120
  121 RFAPVVSAIY PVLTCNPNAP KDAIPNFENA LDVFEVELGK RGTPYFAGQH IGIVDYMIWP 180
  181 WFERFPSMKI NTEQKYELDT KRFEKLLKWR DLMTQDEVVQ KTALDVQLHA EFQKSKTLGN 240
  241 PQYDIAFKGT P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..251] PSI-BLAST 39.69897 Class omega GST

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • antioxidant activity
    		•  3.26520127994042 bayes_pls_golite062009
  • peroxidase activity
    		•  2.96616905270619 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  2.96616905270619 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  2.12777217096121 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  1.96134566495756 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  1.84498211544043 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  1.66635539173786 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.14955061683324 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • maleylacetoacetate isomerase activity
    		•  0.426921894831614 bayes_pls_golite062009
  • binding
    		•  0.419658151482326 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.314980210547407 bayes_pls_golite062009
  • protein binding
    		•  0.034515546627104 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle