Protein Overview: exo70-PA

General Information:
Name(s) found:	exo70-PA / FBpp0076339 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|33112290\|sp\|Q9VSJ8.2\|EXOC7_DROME RecName: Full=Exocyst complex component 7; AltName: Full=Exocyst complex component Exo70 [NCBI NR] gi\|28574393\|ref\|NP_648222.3\| exo70 [Drosophila melanogaster] [NCBI NR] gi\|28380567\|gb\|AAF50421.2\| exo70 [Drosophila melanogaster] [NCBI NR] Exocyst complex component 7 OS=Drosophila melanogaster GN=Exo70 PE=1 SV=2 [Swiss-Prot] (Q9VSJ8) 70 kDa exocyst complex protein [Swiss-Prot] The gene exo70 is referred to in FlyBase by the symbol Dmel\exo70 (CG7127, FBgn0035892). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8404953..8409011. It has the cytological map location 66C11. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle docking during exocytosis; vesicle-mediated transport; exocytosis; synaptic vesicle targeting. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG7127-PA translation from_gene[CG7127 exo70 FBgn0035892] seq_release:3 mol_weight=80027 cds_boundaries:(3L:8,370,671..8,374,525[+]) aa_length:693 transcript_info:[CG7127-RA seq_release:3] gene_info:[gene symbol:exo70 FBgn0035892 gene_boundaries:(3L:8 [hmr_yeast5_DM3-1_pombe.fasta] CG7127-PA [Drosophila melanogaster]gi\|28574393\|ref\|NP_648222.3\| CG7127-PA [Drosophila melanogaster]gi\|33112290\|sp\|Q9VSJ8\|EX70_DROME 70 kDa exocyst complex protein [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(8405061..8405108,8405162..8405327,8405398..8405909,8407318..8407382,8407445..8408175,8408235..8408557,8408627..8408760,8408816..8408918); ID=FBpp0076339; name=exo70-PA; parent=FBgn0035892,FBtr0076612; dbxref=FlyBase:FBpp0076339,F [fly-100309-contam.fasta] CG7127-PA [Drosophila melanogaster] [nr-271106-contam.fasta] exo70 CG7127-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Exocyst complex component 7 (Exocyst complex component Exo70) [nr-271106-contam.fasta] type=protein; loc=3L:join(8405061..8405108,8405162..8405327,8405398..8405909,8407318..8407382,8407445..8408175,8408235..8408557,8408627..8408760,8408816..8408918); ID=FBpp0076339; name=exo70-PA; parent=FBgn0035892,FBtr0076612; dbxref=FlyBase:FBpp0076339,FlyBase_Annotation_IDs:CG7127-PA,GB_protein:AAF50421.2,REFSEQ:NP_648222,GB_protein:AAF50421; MD5=1918d886ccce83de7541311e0b8296d1; length=693; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(8405061..8405108,8405162..8405327,8405398..8405909,8407318..8407382,8407445..8408175,8408235..8408557,8408627..8408760,8408816..8408918); ID=FBpp0076339; name=exo70-PA; parent=FBgn0035892,FBtr0076612; dbxref=FlyBase:FBpp0076339,FlyBase_Annotation_IDs:CG7127-PA,GB_protein:AAF50421.2,REFSEQ:NP_648222,GB_protein:AAF50421; MD5=1918d886ccce83de7541311e0b8296d1; length=693; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Exocyst complex component 7 OS=Drosophila melanogaster GN=exo70 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(8405061..8405108,8405162..8405327,8405398..8405909,8407318..8407382,8407445..8408175,8408235..8408557,8408627..8408760,8408816..8408918); ID=FBpp0076339; name=exo70-PA; parent=FBgn0035892,FBtr0076612; dbxref=FlyBase:FBpp0076339,FlyBase_Annotation_IDs:CG7127-PA,GB_protein:AAF50421.2,REFSEQ:NP_648222,GB_protein:AAF50421,FlyMine:FBpp0076339,modMine:FBpp0076339; MD5=1918d886ccce83de7541311e0b8296d1; length=693; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(8411961..8412008,8412062..8412227,8412298..8412809,8414218..8414282,8414345..8415075,8415135..8415457,8415527..8415660,8415716..8415818); ID=FBpp0076339; name=Exo70-PA; parent=FBgn0266667,FBtr0076612; dbxref=FlyBase:FBpp0076339,FlyBase_Annotation_IDs:CG7127-PA,GB_protein:AAF50421.2,REFSEQ:NP_648222,GB_protein:AAF50421,FlyMine:FBpp0076339,modMine:FBpp0076339; MD5=1918d886ccce83de7541311e0b8296d1; length=693; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(8411961..8412008,8412062..8412227,8412298..8412809,8414218..8414282,8414345..8415075,8415135..8415457,8415527..8415660,8415716..8415818); ID=FBpp0076339; name=Exo70-PA; parent=FBgn0266667,FBtr0076612; dbxref=FlyBase:FBpp0076339,FlyBase_Annotation_IDs:CG7127-PA,GB_protein:AAF50421.2,REFSEQ:NP_648222,GB_protein:AAF50421,FlyMine:FBpp0076339,modMine:FBpp0076339; MD5=1918d886ccce83de7541311e0b8296d1; length=693; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0076339 type=protein; loc=3L:join(8411961..8412008,8412062..8412227,8412298..8412809,8414218..8414282,8414345..8415075,8415135..8415457,8415527..8415660,8415716..8415818); ID=FBpp0076339; name=Exo70-PA; parent=FBgn0266667,FBtr0076612; dbxref=FlyBase:FBpp0076339,FlyBase_Annotation_IDs:CG7127-PA,GB_protein:AAF50421.2,REFSEQ:NP_648222,GB_protein:AAF50421,FlyMine:FBpp0076339,modMine:FBpp0076339; MD5=1918d886ccce83de7541311e0b8296d1; length=693; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(8411961..8412008,8412062..8412227,8412298..8412809,8414218..8414282,8414345..8415075,8415135..8415457,8415527..8415660,8415716..8415818); ID=FBpp0076339; name=Exo70-PA; parent=FBgn0266667,FBtr0076612; dbxref=FlyBase:FBpp0076339,FlyBase_Annotation_IDs:CG7127-PA,GB_protein:AAF50421.2,REFSEQ:NP_648222,GB_protein:AAF50421,UniProt/Swiss-Prot:Q9VSJ8,FlyMine:FBpp0076339,modMine:FBpp0076339; MD5=1918d886ccce83de7541311e0b8296d1; length=693; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	693 amino acids
Gene Ontology:
Cellular Component:	exocyst [ISS][NAS]
Biological Process:	synaptic vesicle targeting [ISS][NAS] synaptic vesicle docking during exocytosis [ISS][NAS] vesicle-mediated transport [ISS] exocytosis [ISS] neurotransmitter secretion [NAS]
Molecular Function:	neurotransmitter transporter activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNLDSSLQA HNKLEKEATN LALLKDRVDK YHDLSTQMSS ILTIFEKRLG NLEQTILPVY  60
   61 QETEQLQKRQ QNLEATLNCL ESVLSHYDVS QEVCQLIHQG PVEGNISVFL DALAKLRDAN 120
  121 DYFRHNNSQS VELENVTSLF NTGCEGLSQH YSMLLKKHSA PLKPVELLDL IYIEDDSSDE 180
  181 YTSFRQLSQT TREELYTISH WLEQNLREYT NIYATERGEV VLRSLQLLKD HQKSNSWGHE 240
  241 ALRPRHSGRQ TEPKKTTSAR LQQIFEKKAN KLYLRATQTI EQSTGFSIKK ASSHSDHLTS 300
  301 EDLMDGDQEL DKYLVMLLGL QRLLNWERAI MIDIIPQSKH NEVFATLAYN AIDLVVKDAE 360
  361 AITQRILRCI SRKEWTSALG IFSALKRVIL LQPDIDRTYD PAQREQLKKV LKKLQHTGAK 420
  421 ALEHFLDVVK GESSTNIVGQ SNVPKDATVH ELTSNTIWFI EHLYDHFDVI GSILAQDVLY 480
  481 STQLDTILMK KALPVEERNK ALLAIYIKKA LAELNLSIMN KCEQYNDQAT KHLFRLNNIH 540
  541 YILKSLQRSN LIDLVTLAEP ECEHSYMEMI RELKASYQKT WSKMLVGIYS LDELPKPVAG 600
  601 KVKDKDRSVL KERFSNFNKD FEEACKIQRG ISIPDVILRE GIKRDNVEHI LPIYNRFYEI 660
  661 YSGVHFSKNP DKYVKYRQHE INAMLSKLFD DSA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: exo70-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: