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Protein Overview: Dbi-PA, Dbi-PB

General Information:
Name(s) found: Dbi-PB / FBpp0076625 [FlyBase]
Dbi-PA / FBpp0076624 [FlyBase]
Description(s) found:
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  • gi|7295286|gb|AAF50607.1| Diazepam-binding inhibitor, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|549853|gb|AAA21650.1| diazepam binding inhibitor [NCBI NR]
  • gi|549851|gb|AAA21649.1| diazepam binding inhibitor [NCBI NR]
  • gi|24659814|ref|NP_523952.2| Diazepam-binding inhibitor, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|24659809|ref|NP_729218.1| Diazepam-binding inhibitor, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|23094045|gb|AAN12074.1| Diazepam-binding inhibitor, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|17944575|gb|AAL48175.1| RH39533p [Drosophila melanogaster] [NCBI NR]
  • pir||A56041 endozepine - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|1168273|sp|P42281.1|ACBP_DROME RecName: Full=Acyl-CoA-binding protein homolog; Short=ACBP; AltName: Full=Diazepam-binding inhibitor homolog; Short=DBI [NCBI NR]
  • Acyl-CoA-binding protein homolog OS=Drosophila melanogaster GN=Dbi PE=2 SV=1 [Swiss-Prot]
  • The gene Diazepam-binding inhibitor is referred to in FlyBase by the symbol Dmel\Dbi (CG8627, FBgn0010387). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:7124965..7126563. It has the cytological map location 65E4. Based on sequence similarity, it is predicted to have molecular function</span>: diazepam binding; enzyme inhibitor activity; acyl-CoA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cellular acyl-CoA homeostasis. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG8627-PA translation from_gene[CG8627 Dbi FBgn0010387] seq_release:3 mol_weight=9557 cds_boundaries:(3L:7,092,195..7,092,893[+]) aa_length:86 transcript_info:[CG8627-RA seq_release:3] gene_info:[gene symbol:Dbi FBgn0010387 gene_boundaries:(3L:7,091,4 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG8627-PB translation from_gene[CG8627 Dbi FBgn0010387] seq_release:3 mol_weight=9557 cds_boundaries:(3L:7,092,195..7,092,893[+]) aa_length:86 transcript_info:[CG8627-RB seq_release:3] gene_info:[gene symbol:Dbi FBgn0010387 gene_boundaries:(3L:7,091,4 [hmr_yeast5_DM3-1_pombe.fasta]
  • (P42281) Acyl-CoA-binding protein homolog (ACBP) (Diazepam binding inhibitor homolog) (DBI) [DrosMelano7227.FASTAC.txt]
  • (AE003560) Dbi gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8627-PB, isoform B [Drosophila melanogaster]gi|7295286|gb|AAF50607.1| CG8627-PA, isoform A [Drosophila melanogaster]gi|17944575|gb|AAL48175.1| RH39533p [Drosophila melanogaster]gi|24659809|ref|NP_729218.1| CG8627-PA [Drosophila melanogaster]gi|24659 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074; MD5=2d347ab8 [fly-100309-contam.fasta]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607; MD5=2d347ab8 [fly-100309-contam.fasta]
  • diazepam binding inhibitor [nr-271106-contam.fasta]
  • Diazepam-binding inhibitor CG8627-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Diazepam-binding inhibitor CG8627-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG8627-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RH39533p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Acyl-CoA-binding protein homolog (ACBP) (Diazepam-binding inhibitor homolog) (DBI) [nr-271106-contam.fasta]
  • CG8627-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074,FlyMine:FBpp0076625,modMine:FBpp0076625; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(7125766..7125777,7126219..7126467); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074,FlyMine:FBpp0076625,modMine:FBpp0076625; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074,FlyMine:FBpp0076625,modMine:FBpp0076625; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0076625 type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074,FlyMine:FBpp0076625,modMine:FBpp0076625; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0076624 type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076625; name=Dbi-PB; parent=FBgn0010387,FBtr0076916; dbxref=FlyBase:FBpp0076625,FlyBase_Annotation_IDs:CG8627-PB,GB_protein:AAN12074.1,REFSEQ:NP_523952,GB_protein:AAN12074,UniProt/Swiss-Prot:P42281,FlyMine:FBpp0076625,modMine:FBpp0076625; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:join(7132666..7132677,7133119..7133367); ID=FBpp0076624; name=Dbi-PA; parent=FBgn0010387,FBtr0076915; dbxref=FlyBase:FBpp0076624,FlyBase_Annotation_IDs:CG8627-PA,GB_protein:AAF50607.1,REFSEQ:NP_729218,GB_protein:AAF50607,UniProt/Swiss-Prot:P42281; MD5=2d347ab8e1769a409ed8d6f2d9b733da; length=86; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 86 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cellular acyl-CoA homeostasis [ISS][NAS]
    Molecular Function: diazepam binding [ISS]
    acyl-CoA binding [ISS][NAS][TAS]
    enzyme inhibitor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSEQFNAAA EKVKSLTKRP SDDEFLQLYA LFKQASVGDN DTAKPGLLDL KGKAKWEAWN  60
   61 KQKGKSSEAA QQEYITFVEG LVAKYA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] PSI-BLAST 27.522879 No description for 2cb8A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle