Protein Overview: tow-PA

General Information:
Name(s) found:	tow-PA / FBpp0076605 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24659615\|ref\|NP_648061.1\| target of wingless, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23094031\|gb\|AAF50636.2\| target of wingless, isoform A [Drosophila melanogaster] [NCBI NR] gi\|21064235\|gb\|AAM29347.1\| GH12583p [Drosophila melanogaster] [NCBI NR] The gene target of wingless is referred to in FlyBase by the symbol Dmel\tow (CG14821, FBgn0035719). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:6936056..6941770. It has the cytological map location 65D3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: establishment of planar polarity; imaginal disc-derived wing hair organization. 11 alleles are reported. The phenotypes of these alleles are annotated with: anterior wing margin; wing blade; scutellum. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG14821-PA translation from_gene[CG14821 CG14821 FBgn0035719] seq_release:3 mol_weight=38140 cds_boundaries:(3L:6,906,064..6,908,031[+]) aa_length:347 transcript_info:[CG14821-RA seq_release:3] gene_info:[gene symbol:CG14821 FBgn0035719 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta] (Q9VRZ4) CG14821 protein (GH12583p) [DrosMelano7227.FASTAC.txt] CG14821-PA [Drosophila melanogaster]gi\|21064235\|gb\|AAM29347.1\| GH12583p [Drosophila melanogaster]gi\|24659615\|ref\|NP_648061.1\| CG14821-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(6939635..6939658,6940348..6941015,6941086..6941209,6941378..6941605); ID=FBpp0076605; name=tow-PA; parent=FBgn0035719,FBtr0076895; dbxref=GB_protein:AAF50636.2,FlyBase:FBpp0076605,FlyBase_Annotation_IDs:CG14821-PA,REFSEQ:NP_64806 [fly-100309-contam.fasta] GH12583p [Drosophila melanogaster] [nr-271106-contam.fasta] CG14821-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(6939635..6939658,6940348..6941015,6941086..6941209,6941378..6941605); ID=FBpp0076605; name=tow-PA; parent=FBgn0035719,FBtr0076895; dbxref=GB_protein:AAF50636.2,FlyBase:FBpp0076605,FlyBase_Annotation_IDs:CG14821-PA,REFSEQ:NP_648061,GB_protein:AAF50636; MD5=805a34505de6046ec7beac52c2c06a88; length=347; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(6939635..6939658,6940348..6941015,6941086..6941209,6941378..6941605); ID=FBpp0076605; name=tow-PA; parent=FBgn0035719,FBtr0076895; dbxref=GB_protein:AAF50636.2,FlyBase:FBpp0076605,FlyBase_Annotation_IDs:CG14821-PA,REFSEQ:NP_648061,GB_protein:AAF50636; MD5=805a34505de6046ec7beac52c2c06a88; length=347; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] GH12583p OS=Drosophila melanogaster GN=tow PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
Organism:	Drosophila melanogaster
Length:	347 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	establishment of planar polarity [IGI] imaginal disc-derived wing hair organization [IMP] negative regulation of smoothened signaling pathway [IMP]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDKKIDEGP DYDSASETEI ALEEARLNAL RQHWESASIT ASICSSASRS LQTTPIRQVQ  60
   61 VPLKQPPRGA GLLIQPSSAS AVTASTSSSS SSTIVALPTT EYLPQHVLTG RQVVQQQQQQ 120
  121 QQQQAAVLYQ QQQQQLILLP QLDPNVVNTS TAAAAAQLVQ LQQQHQQQQQ QLQLQQQQQL 180
  181 QLNQQQQQQL YQQQQQQYLL TLPAGSKPQS VSPKRLIYGG PAATTLLCAT GIKCNAPETY 240
  241 EPPTAPHSQI QQQQPPPPPP GAYYGEMMHG VQAAPAAEYK FPPAISVQRL APQVQRQLRE 300
  301 TQELIKDSCP QLYAAGYGSP GPPIRNPSRN PTRTRPTLET QFSQELS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: tow-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: