Protein Overview: Srp54k-PA

General Information:
Name(s) found:	Srp54k-PA / FBpp0076872 [FlyBase]
Description(s) found: Found 22 descriptions. SHOW ALL	The gene Signal recognition particle protein 54k is referred to in FlyBase by the symbol Dmel\Srp54k (CG4659, FBgn0010747). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:5145669..5147877. It has the cytological map location 64C7. Based on sequence similarity, it is predicted to have molecular function</span>: signal sequence binding; 7S RNA binding. There is experimental evidence that it is involved in the biological process</span>: lysosome organization; negative regulation of autophagy. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	508 amino acids
Gene Ontology:
Cellular Component:	signal recognition particle, endoplasmic reticulum targeting [ISS]
Biological Process:	lysosome organization [IMP] SRP-dependent cotranslational protein targeting to membrane [ISS] SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition [ISS] negative regulation of autophagy [IMP]
Molecular Function:	GTP binding [IEA] protein binding [IEA] 7S RNA binding [ISS] nucleoside-triphosphatase activity [IEA] signal sequence binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLADLGRKI TTALHSLSKA TVINEEALNS MLKEICAALL EADVNIRLVK QLRENVRAVI  60
   61 DFDEMAGGLN KRRMIQSAVF KELVKLVDPG VKPYQPIKGK ANVVMFVGLQ GSGKTTTCTK 120
  121 LAYHYQKRNW KSCLVCADTF RAGAYDQVKQ NATKARIPFY GSYTEIDPVV IAQDGVDMFK 180
  181 REGFEMIIVD TSGRHKQEES LFEEMLAVSN AVSPDNIIFV MDATIGQACE AQAKAFKDKV 240
  241 DIGSVIITKL DGHAKGGGAL SAVAATQSPI IFIGTGEHID DLEPFKTKPF VSKLLGMGDI 300
  301 EGLIDKVNEL KLDGNDELLE KIKHGHFTIR DMYEQFQNIM KMGPFSQFMN MIPGFSQDFM 360
  361 TKGGEQESMA RVKRMMTMMD SMSDNELDNR DGAKLFSKQP NRCVRVAQGA GVMEREVKEL 420
  421 IAHYTKFSAV VKKMGGVKGL FKQGDMTKNV NPTQMAKLNQ QIAKMIDPRM LQQMGGVGGI 480
  481 QNMMRQLQQG AAGGLGGLGN LMSGFGGK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.87

Protein Overview: Srp54k-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: