Protein Overview: tipE-PA, tipE-PB

General Information:
Name(s) found:	tipE-PB / FBpp0073076 [FlyBase] tipE-PA / FBpp0073075 [FlyBase]
Description(s) found: Found 39 descriptions. SHOW ALL	The gene temperature-induced paralytic E is referred to in FlyBase by the symbol Dmel\tipE (CG1232, FBgn0003710). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4188530..4193788. It has the cytological map location 64A10. There is experimental evidence that it has the molecular function</span>: sodium channel regulator activity. There is experimental evidence that it is involved in the biological process</span>: male courtship behavior, veined wing generated song production; cellular response to heat; positive regulation of sodium ion transport via voltage-gated sodium channel activity. 16 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene temperature-induced paralytic E is referred to in FlyBase by the symbol Dmel\tipE (CG1232, FBgn0003710). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4188530..4193788. It has the cytological map location 64A10. There is experimental evidence that it has the molecular function</span>: sodium channel regulator activity. There is experimental evidence that it is involved in the biological process</span>: male courtship behavior, veined wing generated song production; cellular response to heat; positive regulation of sodium ion transport via voltage-gated sodium channel activity. 16 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	452 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IDA][NAS] plasma membrane [IDA][ISS][TAS]
Biological Process:	sodium ion transport [NAS] cellular response to heat [IDA] male courtship behavior, veined wing generated song production [IMP] positive regulation of sodium ion transport via voltage-gated sodium channel activity [IDA]
Molecular Function:	sodium channel regulator activity [IDA] voltage-gated sodium channel activity [ISS][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDEQDKRTG KEKLLFYTTA FFILLGTFSL FAFLFLVPFV IEPAFTTIFM QFEEVPALCE  60
   61 TYDTEIYYGA KNCSWSSCRE GCTKDIYTCT QIRVNYRLNL YNFTDEFNFT EYHINLKEAE 120
  121 RILPPVKRTD RYERALRSDY EYDNLGGGTG LDIDLGAGRM EQLNFGDADG SNGYLIEDSE 180
  181 DTRGLSASGT LISDERRPFD EISELNEGLM GNRSMYYYVG ARLFPNVKGC GYPPMLNCTI 240
  241 WLKRYTKIGM KFPCYYSKVD PSLVISDLDY WQNTLNLVYS MAIPIPSFII SVIYLTYAYF 300
  301 KIYNEDEETA PLDKNAEDMD IDDIDAVDDS DGAVLADNVA GSQIINMDST TNDSCLEGVL 360
  361 PNGGPGMTAS ISQGGSVTTP GPYIAQSPAG SQMTPNSEIN SFGHQLKVQM ADELSRDSLE 420
  421 NGAISTSNSV QGNLSKTMTT SISTPPGPTA AV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: tipE-PA, tipE-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: