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Protein Overview: Awh-PB

General Information:
Name(s) found: Awh-PB / FBpp0073014 [FlyBase]
Description(s) found:
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  • gi|94400621|gb|ABF17921.1| FI01007p [Drosophila melanogaster] [NCBI NR]
  • gi|62510367|sp|Q8IRC7.1|AWH_DROME RecName: Full=LIM/homeobox protein Awh; AltName: Full=Protein arrowhead [NCBI NR]
  • gi|24656992|ref|NP_728906.1| arrowhead, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|23092944|gb|AAN11572.1| arrowhead, isoform B [Drosophila melanogaster] [NCBI NR]
  • LIM/homeobox protein Awh OS=Drosophila melanogaster GN=Awh PE=1 SV=1 [Swiss-Prot]
  • The gene Arrowhead is referred to in FlyBase by the symbol Dmel\Awh (CG1072, FBgn0013751). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3846153..3861697. It has the cytological map location 63F4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc development. 36 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; organ system; peripheral nervous system; thoracic segment; nervous system; appendage segment; imaginal precursor; anterior vertical bristle; salivary gland imaginal ring; intracellular organelle part; larval abdominal segment; dorsal thoracic disc; spiracle; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG1072-PB translation from_gene[CG1072 Awh FBgn0013751] seq_release:3 mol_weight=31032 cds_boundaries:(3L:3,827,371..3,841,578[+]) aa_length:275 transcript_info:[CG1072-RB seq_release:3] gene_info:[gene symbol:Awh FBgn0013751 gene_boundaries:(3L:3,826 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8IRC7) CG1072-PB [DrosMelano7227.FASTAC.txt]
  • CG1072-PB, isoform B [Drosophila melanogaster]gi|24656992|ref|NP_728906.1| CG1072-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_p [fly-100309-contam.fasta]
  • Arrowhead CG1072-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • FI01007p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LIM/homeobox protein Awh (Protein arrowhead) [nr-271106-contam.fasta]
  • CG1072-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_protein:AAN11572.1,REFSEQ:NP_728906,GB_protein:AAN11572; MD5=063aae0b29cfbba0046e417ab8def63b; length=275; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_protein:AAN11572.1,REFSEQ:NP_728906,GB_protein:AAN11572; MD5=063aae0b29cfbba0046e417ab8def63b; length=275; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_protein:AAN11572.1,REFSEQ:NP_728906,GB_protein:AAN11572,FlyMine:FBpp0073014,modMine:FBpp0073014; MD5=063aae0b29cfbba0046e417ab8def63b; length=275; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_protein:AAN11572.1,REFSEQ:NP_728906,GB_protein:AAN11572,FlyMine:FBpp0073014,modMine:FBpp0073014; MD5=063aae0b29cfbba0046e417ab8def63b; length=275; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_protein:AAN11572.1,REFSEQ:NP_728906,GB_protein:AAN11572,FlyMine:FBpp0073014,modMine:FBpp0073014; MD5=063aae0b29cfbba0046e417ab8def63b; length=275; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0073014 type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_protein:AAN11572.1,REFSEQ:NP_728906,GB_protein:AAN11572,FlyMine:FBpp0073014,modMine:FBpp0073014; MD5=063aae0b29cfbba0046e417ab8def63b; length=275; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(3846742..3846747,3857942..3858123,3859167..3859384,3860190..3860423,3860636..3860761,3860891..3860952); ID=FBpp0073014; name=Awh-PB; parent=FBgn0013751,FBtr0073156; dbxref=FlyBase:FBpp0073014,FlyBase_Annotation_IDs:CG1072-PB,GB_protein:AAN11572.1,REFSEQ:NP_728906,GB_protein:AAN11572,UniProt/Swiss-Prot:Q8IRC7,FlyMine:FBpp0073014,modMine:FBpp0073014; MD5=063aae0b29cfbba0046e417ab8def63b; length=275; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 275 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: imaginal disc development [IMP]
    regulation of transcription, DNA-dependent [IEA][ISS]
    regulation of transcription [IEA]
    Molecular Function: transcription factor activity [ISS]
    zinc ion binding [IEA]
    protein binding [ISS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTELRSCAA CGEPISDRFF LEVGGCSWHA HCLRCCMCMC PLDRQQSCFI RERQVYCKAD  60
   61 YSKNFGAKCS KCCRGISASD WVRRARELVF HLACFACDQC GRQLSTGEQF ALMDDRVLCK 120
  121 AHYLETVEGG TTSSDEGCDG DGYHKSKTKR VRTTFTEEQL QVLQANFQID SNPDGQDLER 180
  181 IASVTGLSKR VTQVWFQNSR ARQKKHIHAG KNKIREPEGS SFARHINLQL TYSFQNNAQN 240
  241 PMHLNGSKAG LYPTHESSMD ELSQDSSVHC MPSEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle