Protein Overview: CG12034-PA

General Information:
Name(s) found:	CG12034-PA / FBpp0072907 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|32172461\|sp\|Q9VZS6.2\|NSMA_DROME RecName: Full=Putative neutral sphingomyelinase [NCBI NR] gi\|23092890\|gb\|AAF47741.2\| CG12034 [Drosophila melanogaster] [NCBI NR] gi\|21357231\|ref\|NP_647790.1\| CG12034 [Drosophila melanogaster] [NCBI NR] gi\|15291739\|gb\|AAK93138.1\| LD24865p [Drosophila melanogaster] [NCBI NR] Putative neutral sphingomyelinase OS=Drosophila melanogaster GN=CG12034 PE=2 SV=2 [Swiss-Prot] This gene is referred to in FlyBase by the symbol Dmel\CG12034 (CG12034, FBgn0035421). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3219124..3220925. It has the cytological map location 63B14. Based on sequence similarity, it is predicted to have molecular function</span>: sphingomyelin phosphodiesterase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: sphingomyelin metabolic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG12034-PA translation from_gene[CG12034 CG12034 FBgn0035421] seq_release:3 mol_weight=49643 cds_boundaries:(3L:3,199,933..3,201,344[+]) aa_length:442 transcript_info:[CG12034-RA seq_release:3] gene_info:[gene symbol:CG12034 FBgn0035421 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta] (Q9VZS6) Putative neutral sphingomyelinase (EC 3.1.4.12) [DrosMelano7227.FASTAC.txt] CG12034-PA [Drosophila melanogaster]gi\|15291739\|gb\|AAK93138.1\| LD24865p [Drosophila melanogaster]gi\|21357231\|ref\|NP_647790.1\| CG12034-PA [Drosophila melanogaster]gi\|32172461\|sp\|Q9VZS6\|NSMA_DROME Putative neutral sphingomyelinase [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741; MD5=a21 [fly-100309-contam.fasta] CG12034-PA [Drosophila melanogaster] [nr-271106-contam.fasta] LD24865p [Drosophila melanogaster] [nr-271106-contam.fasta] Putative neutral sphingomyelinase [nr-271106-contam.fasta] type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741; MD5=a21cb219e011196fb36acb192dd3ba56; length=442; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741; MD5=a21cb219e011196fb36acb192dd3ba56; length=442; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Putative neutral sphingomyelinase OS=Drosophila melanogaster GN=CG12034 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741,FlyMine:FBpp0072907,modMine:FBpp0072907; MD5=a21cb219e011196fb36acb192dd3ba56; length=442; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741,FlyMine:FBpp0072907,modMine:FBpp0072907; MD5=a21cb219e011196fb36acb192dd3ba56; length=442; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741,FlyMine:FBpp0072907,modMine:FBpp0072907; MD5=a21cb219e011196fb36acb192dd3ba56; length=442; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0072907 type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741,FlyMine:FBpp0072907,modMine:FBpp0072907; MD5=a21cb219e011196fb36acb192dd3ba56; length=442; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(3219304..3219344,3219431..3220718); ID=FBpp0072907; name=CG12034-PA; parent=FBgn0035421,FBtr0073043; dbxref=FlyBase:FBpp0072907,FlyBase_Annotation_IDs:CG12034-PA,GB_protein:AAF47741.2,REFSEQ:NP_647790,GB_protein:AAF47741,UniProt/Swiss-Prot:Q9VZS6,FlyMine:FBpp0072907,modMine:FBpp0072907; MD5=a21cb219e011196fb36acb192dd3ba56; length=442; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	442 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	sphingomyelin metabolic process [ISS]
Molecular Function:	sphingomyelin phosphodiesterase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLELNILT LNIWGIPYVS SDRRPRIDAI CKELASGKYD IVSLQEVWAQ EDSELLQKGT  60
   61 EAVLPHSHYF HSGVMGAGLL VLSKYPILGT LFHAWSVNGY FHRIQHADWF GGKGVGLCRI 120
  121 LVGGQMVHLY NAHLHAEYDN ANDEYKTHRV IQAFDTAQFI EATRGNSALQ ILAGDLNAQP 180
  181 QDISYKVLLY TSKMLDSCDS DSFRTNECEH NSYTSKQARE RNPLGIRIDH IFVRGGDHVN 240
  241 AEIAEYKLPF PERVPGEKFS FSDHEAVMAK LKLFKLEPRS EEPVATIEVN CLVEDGETCS 300
  301 VREVGAGDAL TGEDDQSSQH QPEIQCNGSS TSIQSMPAAR TAALLEALAL CDASLLQLNT 360
  361 DRILYYSAAT FLFVLLVLLV EFTAPVGMRT IFLLLKFIVF GVILFCVFMA SIWNYMERNG 420
  421 VLQGKKSMEV MLHHAQKYEY FY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CG12034-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: