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Protein Overview: CG12079-PA

General Information:
Name(s) found: CG12079-PA / FBpp0072975 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG12079 (CG12079, FBgn0035404). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3158490..3159573. It has the cytological map location 63B7. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 265 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex I [ISS]
    Biological Process: oxidation reduction [IEA]
    Molecular Function: NADH dehydrogenase activity [ISS]
    NADH dehydrogenase (ubiquinone) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALIRNLGA RAAVAALSAK HVVPAAGSTA LRMASTTPVE PKKADKPTVR QPDAVARSHL  60
   61 SDFGRYVAEC LPKYVQKVQL TAGDELEVLI APEGVVPVLQ FLKDHHQAQF TNLVDIAGVD 120
  121 VPCRKNRFEV VYNLLSLRYN SRIRVKTYTD ELTPLDSACE VHKAANWYER EIWDMYGVFF 180
  181 ANHPDLRRIL TDYGFEGHPQ RRDFPLSGYV ELRYDDEKKR VVCEPLELAQ EFRKFDLSAP 240
  241 WEQFPNFRNA NPPAEVVPPQ APAKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] deduced N/A No confident structure predictions are available.
    2 View Details [83..265] PSI-BLAST 31.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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