Protein Overview: spz5-PA

General Information:
Name(s) found:	spz5-PA / FBpp0072881 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7292286\|gb\|AAF47694.1\| CG9972 [Drosophila melanogaster] [NCBI NR] gi\|21357861\|ref\|NP_647753.1\| CG9972 [Drosophila melanogaster] [NCBI NR] gi\|15291781\|gb\|AAK93159.1\| LD26258p [Drosophila melanogaster] [NCBI NR] The gene spatzle 5 is referred to in FlyBase by the symbol Dmel\spz5 (CG9972, FBgn0035379). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:2883638..2892164. It has the cytological map location 63A1. There is experimental evidence that it has the molecular function</span>: growth factor activity. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance; regulation of cell death; axon guidance; nervous system development; regulation of neuronal synaptic plasticity in response to neurotrophin; central nervous system formation. 4 alleles are reported. The phenotypes of these alleles are annotated with: SNa; ISNb; ISNd. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG9972-PA translation from_gene[CG9972 CG9972 FBgn0035379] seq_release:3 mol_weight=42827 cds_boundaries:(3L:2,864,723..2,869,792[-]) aa_length:387 transcript_info:[CG9972-RA seq_release:3] gene_info:[gene symbol:CG9972 FBgn0035379 gene_boundaries:(3L [hmr_yeast5_DM3-1_pombe.fasta] (Q9VZX1) CG9972 protein (LD26258P) [DrosMelano7227.FASTAC.txt] (AE003476) CG9972 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG9972-PA [Drosophila melanogaster]gi\|15291781\|gb\|AAK93159.1\| LD26258p [Drosophila melanogaster]gi\|21357861\|ref\|NP_647753.1\| CG9972-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(2884091..2884259,2885896..2886408,2886689..2886952,2888890..2889044,2889101..2889163); ID=FBpp0072881; name=CG9972-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:A [fly-100309-contam.fasta] CG9972-PA [Drosophila melanogaster] [nr-271106-contam.fasta] LD26258p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(2884091..2884259,2885896..2886408,2886689..2886952,2888890..2889044,2889101..2889163); ID=FBpp0072881; name=CG9972-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:AAF47694.1,REFSEQ:NP_647753,GB_protein:AAF47694; MD5=d6d9328b35df1dbf2ee4e345c5e12864; length=387; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(2884091..2884259,2885896..2886408,2886689..2886952,2888890..2889044,2889101..2889163); ID=FBpp0072881; name=spz5-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:AAF47694.1,REFSEQ:NP_647753,GB_protein:AAF47694; MD5=d6d9328b35df1dbf2ee4e345c5e12864; length=387; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] LD26258p OS=Drosophila melanogaster GN=spz5 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(2884091..2884259,2885896..2886408,2886689..2886952,2888890..2889044,2889101..2889163); ID=FBpp0072881; name=spz5-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:AAF47694.1,REFSEQ:NP_647753,GB_protein:AAF47694,FlyMine:FBpp0072881,modMine:FBpp0072881; MD5=d6d9328b35df1dbf2ee4e345c5e12864; length=387; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] LD26258p OS=Drosophila melanogaster GN=spz5 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=3L:complement(join(2889101..2889163,2888890..2889044,2886689..2886952,2885896..2886408,2884091..2884259)); ID=FBpp0072881; name=spz5-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:AAF47694.1,REFSEQ:NP_647753,GB_protein:AAF47694,FlyMine:FBpp0072881,modMine:FBpp0072881; MD5=d6d9328b35df1dbf2ee4e345c5e12864; length=387; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(2889101..2889163,2888890..2889044,2886689..2886952,2885896..2886408,2884091..2884259)); ID=FBpp0072881; name=spz5-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:AAF47694.1,REFSEQ:NP_647753,GB_protein:AAF47694,FlyMine:FBpp0072881,modMine:FBpp0072881; MD5=d6d9328b35df1dbf2ee4e345c5e12864; length=387; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0072881 type=protein; loc=3L:complement(join(2889101..2889163,2888890..2889044,2886689..2886952,2885896..2886408,2884091..2884259)); ID=FBpp0072881; name=spz5-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:AAF47694.1,REFSEQ:NP_647753,GB_protein:AAF47694,FlyMine:FBpp0072881,modMine:FBpp0072881; MD5=d6d9328b35df1dbf2ee4e345c5e12864; length=387; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(2889101..2889163,2888890..2889044,2886689..2886952,2885896..2886408,2884091..2884259)); ID=FBpp0072881; name=spz5-PA; parent=FBgn0035379,FBtr0073011; dbxref=FlyBase:FBpp0072881,FlyBase_Annotation_IDs:CG9972-PA,GB_protein:AAF47694.1,REFSEQ:NP_647753,GB_protein:AAF47694,UniProt/Swiss-Prot:Q9VZX1,FlyMine:FBpp0072881,modMine:FBpp0072881; MD5=d6d9328b35df1dbf2ee4e345c5e12864; length=387; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	387 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	regulation of neuronal synaptic plasticity in response to neurotrophin [IMP] motor axon guidance [IMP] regulation of cell death [IDA] nervous system development [IMP] axon guidance [IMP] central nervous system formation [IMP]
Molecular Function:	growth factor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKSIKRPPP FSCKQVLLTY VILAYTVAAH SSPPPCGLYG APPCQFLPAP PGQTPTCARP  60
   61 GKTYCEHADN YPTYLIKSLV RKWGYEAATL LVDETWEDFA AVAWHDTPVF YDPKSIFPPR 120
  121 DPAAQDFNGY SYQTPFGGNP QRPSGGGNPL FVSNPSTEAP TYLLYTSSGG GHRSGHRYNS 180
  181 QGGGTSSSGG HLYINQSDKS TPYNATLWLK RLVRDLSRKQ RQPDEVQAEV VEPVNEQTEE 240
  241 AEEQDNPAED HPQSKRDVSL NMDLLDIVGV EAPNPLKKRS RTKRQSPGRS TLCQTTSQFI 300
  301 TPQAALNSRG NWMFVVNEQN TARQMVKAEL CASNTCSNLC ELPNGYNSRC EQKFVQKRLI 360
  361 ALQGNGQNLY TDTFWFPSCC VCTIAAN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: spz5-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: