Protein Overview: Mrtf-PB, Mrtf-PA

General Information:
Name(s) found:	Mrtf-PB / FBpp0288506 [FlyBase] Mrtf-PA / FBpp0072821 [FlyBase]
Description(s) found: Found 19 descriptions. SHOW ALL	The gene Myocardin-related transcription factor is referred to in FlyBase by the symbol Dmel\Mrtf (CG32296, FBgn0052296). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:2719685..2766480. It has the cytological map location 62F2-62F3. It is reported to have molecular function</span>: transcription activator activity. There is experimental evidence that it is involved in the biological process</span>: mesodermal cell migration; border follicle cell migration; actin cytoskeleton organization; imaginal disc-derived wing morphogenesis; open tracheal system development. 28 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; embryonic/larval tracheal system; female germline cyst; thoracic segment; extended germ band embryo; portion of tissue; embryonic dorsal branch; embryonic dorsal vessel; embryonic dorsal trunk; embryonic tracheal system; primordium; embryonic ganglionic branch; peripheral nervous system; late extended germ band embryo. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene Myocardin-related transcription factor is referred to in FlyBase by the symbol Dmel\Mrtf (CG32296, FBgn0052296). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:2719685..2766480. It has the cytological map location 62F2-62F3. It is reported to have molecular function</span>: transcription activator activity. There is experimental evidence that it is involved in the biological process</span>: mesodermal cell migration; border follicle cell migration; actin cytoskeleton organization; imaginal disc-derived wing morphogenesis; open tracheal system development. 28 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; embryonic/larval tracheal system; female germline cyst; thoracic segment; extended germ band embryo; portion of tissue; embryonic dorsal branch; embryonic dorsal vessel; embryonic dorsal trunk; embryonic tracheal system; primordium; embryonic ganglionic branch; peripheral nervous system; late extended germ band embryo. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1473 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	mesodermal cell migration [IMP] positive regulation of transcription, DNA-dependent [NAS] imaginal disc-derived wing morphogenesis [IMP] border follicle cell migration [IMP] actin cytoskeleton organization [IMP] open tracheal system development [IMP]
Molecular Function:	nucleic acid binding [IEA] transcription activator activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEGEQRLHA TFLGSSDDGN NSDCYDARQS PPKAIVDSSP LQPAMDKNKE SLKVKLMVRR  60
   61 PHSQLVEQGI IPSLKTSPAI HEQCKQLERA KTSDLLKAKI QQRPNREDLE RLHILEEDEC 120
  121 HIDPSLAEKQ RMLKKARLAD QLNSQIQHRP GPLELIKKNI LHTEKPIEKI VKEGLVSFKA 180
  181 TSEGLLTRPQ HPHSYVTFDD DSLSSESDTR QTPPRLDEAM VATSSSPTDV LQAAAASAGI 240
  241 VTMALTMPTA GQLVVTSPQI LPQQQQPKAI VVKQETANLY EELCQSVTGT TASPVNHLYS 300
  301 PCSLASSTST LSPLSSIASP PPPPMTTTRL HLAPVSVKSD APGKDKNRKK SKSKPVSKAR 360
  361 TIKFHEYKGP PSAAGQKQDQ TQPEETSYQL MLEQQNCLLK FLENLNKNQS IIPAPSAPGV 420
  421 MLPAAPGATN NSITVTTKTV PALASQSAPA PAPISLPNTI SITSSSGGAP LNFGDATMLT 480
  481 PTPAATPTPP TLSLIAAPQQ QLQLHQQHQQ LHQPTPVQHP PPLPSPALSV SSSIPPSPAT 540
  541 SYAESTTSSI TDLARLEKMK VSDLKQHLKR RNLPVSGPKP HLIERLKPYL PLEPLDSNVT 600
  601 PAPTSNNSNT TPEVITISDA MDTSNCGLLE QPPPVTMLVS DASMEHEQMD VVQQQMDNTH 660
  661 PMTLQTILPP QPQTATIILT NEELLREQQR KIDELQRQLQ RSQQELQKIR QRQQQQQHQQ 720
  721 QQTVTAQVVN ALPSQQITLI TTTSNGPQQT LTVMPQQVEK NFPAKVTVKA TGGNSNHKVN 780
  781 GLQQQGSAAK KPASSNSNSN SNISSSNPPP INQKMVVKQQ LEAKIQKQKA AAAAAAQQQQ 840
  841 QQQQQQQQQQ QQQALQQQQQ QQQQQQQVRL LTQKTQTVFI PFNNNNHINN ASAKTTTKKS 900
  901 NVPANNTNTT TATMMQAAKP AAVAAAAASP GNQHHNNLGL LWNEGNQTIL LLGLNDQHMT 960
  961 AHTLGNISLT ATTTTTAAPP AATPVAASTI APPKKILNGH QRTNSLPSIV FPIETKSIIT1020
 1021 QQQLQQLQQQ QQQQQQFQPV QQPKQQQLNQ VDIKPAPAPP PQYEEATKQL AASKAAALNG1080
 1081 LLPLVKIKEE PVQSPAPSAA PLPQTAPLCK RKTASIKSEQ VSDVLDILIK QGELPESAAL1140
 1141 EPITPLTPLP ELSMFNGATP TTAAGGASIV PLVPKLETPV TPVQNLDVAM DTNVQHVGFA1200
 1201 SNQAPNHVFI ESIDMASPLQ TDSSAIDAES VAKTLDIFLE QHHATPPPST PPKSCHSGSE1260
 1261 KPNSPDAKLN HFDEYELLEL MSQQLEMDMG DDSSGYCHAS AAKSSNNNGN LRRDLNPSLQ1320
 1321 PSINELLDAS SPDNVLLNNN TGADVDFDAD SFVAQLSQHV TGNGNSPGVN CNGSIESSSS1380
 1381 AVNSHFGSHS TPMDCDDFES TLNSFMQAVT QPQAGQHVEY ATSTSMANGT GGGMGVDNGT1440
 1441 GGAVDAFNAS GDIFDLFNMD DYKMNWAAGD FTV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.80

Protein Overview: Mrtf-PB, Mrtf-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: