Protein Overview: dos-PA

General Information:
Name(s) found:	dos-PA / FBpp0072803 [FlyBase]
Description(s) found: Found 20 descriptions. SHOW ALL	The gene daughter of sevenless is referred to in FlyBase by the symbol Dmel\dos (CG1044, FBgn0016794). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:2589402..2595590. It has the cytological map location 62E7. There is experimental evidence that it has the molecular function</span>: SH2 domain binding; protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of Ras protein signal transduction; antimicrobial humoral response. 42 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor; photoreceptor cell R7; eye; anterior crossvein; wing vein L4; cone cell; eye photoreceptor cell; ommatidium; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	878 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] plasma membrane [ISS]
Biological Process:	torso signaling pathway [NAS] anterior/posterior axis specification, embryo [TAS] sevenless signaling pathway [TAS] regulation of Ras protein signal transduction [IMP] antimicrobial humoral response [IMP]
Molecular Function:	SH3/SH2 adaptor activity [ISS] protein binding [IPI] SH2 domain binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRTFYEGWL IKSPPTKRIW RARWRRRYFT LKQGEIPEQF CLEYYTDHNC RKLKGVIDLD  60
   61 QCEQVDCGLR LENRKQKFQY MFDIKTPKRT YYLAAETEAD MRDWVNCICQ VCHLHDTKQS 120
  121 NELPLGAVGA DENRTQHTSS SGGLSNSTQN TTTTSLHSSA GTTAPQASVP NAGGSAQLRR 180
  181 PAVIEEQPMP SNAGNNNSDS VYVNTEYSNR ETMLCDANFD QQELLSAAQQ QPPPSPATAL 240
  241 YLNHSALIQA QAAAAAAEQL QQQQQQAARL AVSANGVVRK LPEHLVLTQQ TLAEAAAQQH 300
  301 SSVQASPALS TASGPYIPIS ECFSGSPRFL PGVPLPGADL AIPNNPTTPL NNLDPKFYDT 360
  361 PRSHNNIGLN LTNDQSYSPK ITNLSLQQLA NNNASKQRSD SDSESVFTDD DEWAHPLPLR 420
  421 ENVDRSTRPS DSSIENESFV LTYSQRFSKM PEEGGAIVPP AEKSSKLAGA ASLPEAGDQG 480
  481 TLDKLAKVLK NKNNLILDFK ENEKIPRDLP QLSDTENTSP AIVARRNAHS AFIEESYDIP 540
  541 RSHQQPYYNV NQLLGERPVT SPHNSNPIAA STPNLMAADL GAVAAISAAA NPGLMGEAQA 600
  601 VASSPTSART LPRHCYTNAA PTKMEGNVFR YDFMEQADCP PVNRKLKPKV AGGLPVVEDK 660
  661 PPEEFPAKPP VGVDQLTNKL GAAQLQQPIG PPSVDRKCKP NAYKLGNSAT MSPATRRSSG 720
  721 APLSMVLPHE TDVHSPAAAN AFFHETRTLP RQQHRHHPNS PGSMSVQHQR TASAAAAMMS 780
  781 LTAAAAPKQQ AAAQTEHKLQ YFDLDVTNKP PLLNRSSMSV GNLYSQGGNG ASGMRFAGVE 840
  841 AGGARAPVPS SVVYRSVDFV KTEAFKRIRE ERESSGNK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: dos-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: