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Protein Overview: RpL8-PA, RpL8-PB

General Information:
Name(s) found: RpL8-PB / FBpp0072802 [FlyBase]
RpL8-PA / FBpp0072801 [FlyBase]
Description(s) found:
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  • gi|7292251|gb|AAF47660.1| ribosomal protein L8, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|7292250|gb|AAF47659.1| ribosomal protein L8, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|6318302|gb|AAF06828.1|AF098520_1 ribosomal protein L8 [Drosophila melanogaster] [NCBI NR]
  • gi|51701901|sp|Q9V3G1.1|RL8_DROME RecName: Full=60S ribosomal protein L8 [NCBI NR]
  • gi|48958421|gb|AAT47764.1| RH21963p [Drosophila melanogaster] [NCBI NR]
  • gi|24656124|ref|NP_728756.1| ribosomal protein L8, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|17945835|gb|AAL48964.1| RE37829p [Drosophila melanogaster] [NCBI NR]
  • gi|17864318|ref|NP_524726.1| ribosomal protein L8, isoform A [Drosophila melanogaster] [NCBI NR]
  • 60S ribosomal protein L8 OS=Drosophila melanogaster GN=RpL8 PE=1 SV=1 [Swiss-Prot]
  • The gene Ribosomal protein L8 is referred to in FlyBase by the symbol Dmel\RpL8 (CG1263, FBgn0024939). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:2587450..2588997. It has the cytological map location 62E7. There is experimental evidence that it has the molecular function</span>: SUMO binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle elongation; mitotic spindle organization. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG1263-PA translation from_gene[CG1263 RpL8 FBgn0024939] seq_release:3 mol_weight=27893 cds_boundaries:(3L:2,568,382..2,569,342[+]) aa_length:256 transcript_info:[CG1263-RA seq_release:3] gene_info:[gene symbol:RpL8 FBgn0024939 gene_boundaries:(3L:2,5 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG1263-PB translation from_gene[CG1263 RpL8 FBgn0024939] seq_release:3 mol_weight=27893 cds_boundaries:(3L:2,568,382..2,569,342[+]) aa_length:256 transcript_info:[CG1263-RB seq_release:3] gene_info:[gene symbol:RpL8 FBgn0024939 gene_boundaries:(3L:2,5 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V3G1) CG1263 protein (RE37829p) [DrosMelano7227.FASTAC.txt]
  • (AE003475) RpL8 gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta]
  • (AE003475) RpL8 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG1263-PB, isoform B [Drosophila melanogaster]gi|7292250|gb|AAF47659.1| CG1263-PA, isoform A [Drosophila melanogaster]gi|48958421|gb|AAT47764.1| RH21963p [Drosophila melanogaster]gi|17945835|gb|AAL48964.1| RE37829p [Drosophila melanogaster]gi|24656124 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0024939,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659; MD5=d09e64c [fly-100309-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0024939,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660; MD5=d09e64c [fly-100309-contam.fasta]
  • Ribosomal protein L8 CG1263-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG1263-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • ribosomal protein L8 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Ribosomal protein L8 CG1263-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG1263-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE37829p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • 60S ribosomal protein L8 [nr-271106-contam.fasta]
  • RH21963p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0024939,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0024939,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0024939,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0024939,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • 60S ribosomal protein L8 OS=Drosophila melanogaster GN=RpL8 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0261602,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659,FlyMine:FBpp0072801,modMine:FBpp0072801; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0261602,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0261602,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659,FlyMine:FBpp0072801,modMine:FBpp0072801; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0261602,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0261602,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659,FlyMine:FBpp0072801,modMine:FBpp0072801; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0261602,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0072801 type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0261602,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659,FlyMine:FBpp0072801,modMine:FBpp0072801; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0072802 type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0261602,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072801; name=RpL8-PA; parent=FBgn0261602,FBtr0072924; dbxref=FlyBase:FBpp0072801,FlyBase_Annotation_IDs:CG1263-PA,GB_protein:AAF47659.1,REFSEQ:NP_524726,GB_protein:AAF47659,UniProt/Swiss-Prot:Q9V3G1,FlyMine:FBpp0072801,modMine:FBpp0072801; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:join(2587753..2587890,2588084..2588716); ID=FBpp0072802; name=RpL8-PB; parent=FBgn0261602,FBtr0072925; dbxref=FlyBase:FBpp0072802,FlyBase_Annotation_IDs:CG1263-PB,GB_protein:AAF47660.1,REFSEQ:NP_728756,GB_protein:AAF47660,UniProt/Swiss-Prot:Q9V3G1; MD5=d09e64c3a15edc7f30e4ac2fa02ce592; length=256; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 256 amino acids

    Gene Ontology:
    Cellular Component: cytosolic large ribosomal subunit [ISS]
    Biological Process: mitotic spindle elongation [IMP]
    mitotic spindle organization [IMP]
    translation [ISS]
    Molecular Function: SUMO binding [IPI]
    structural constituent of ribosome [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRVIRAQRK GAGSVFKAHV KKRKGAAKLR SLDFAERSGY IRGVVKDIIH DPGRGAPLAV  60
   61 VHFRDPYRYK IRKELFIAPE GMHTGQFVYC GRKATLQIGN VMPLSQMPEG TIICNLEEKT 120
  121 GDRGRLARTS GNYATVIAHN QDTKKTRVKL PSGAKKVVPS ANRAMVGIVA GGGRIDKPIL 180
  181 KAGRAYHKYK VKRNSWPKVR GVAMNPVEHP HGGGNHQHIG KASTVKRGTS AGRKVGLIAA 240
  241 RRTGRIRGGK GDSKDK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] PSI-BLAST 70.09691 Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. This file, 1S1I, Contains 60S subunit. The 40S Ribosomal Subunit Is In File 1S1H.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle