Protein Overview: Trh-PA

General Information:
Name(s) found:	Trh-PA / FBpp0072534 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	The gene Tryptophan hydroxylase is referred to in FlyBase by the symbol Dmel\Trh (CG9122, FBgn0035187). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1190384..1193169. It has the cytological map location 61F3. There is experimental evidence that it has the molecular function</span>: phenylalanine 4-monooxygenase activity; tryptophan 5-monooxygenase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of circadian sleep/wake cycle, sleep; serotonin biosynthetic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	555 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	serotonin biosynthetic process [IDA] regulation of circadian sleep/wake cycle, sleep [IMP] oxidation reduction [IEA] tryptophan metabolic process [ISS]
Molecular Function:	iron ion binding [IEA] phenylalanine 4-monooxygenase activity [IDA] tryptophan 5-monooxygenase activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASGKSLLG LWLYRSGEQE WAVKQGSPLH QLKKDSTTSG SSSHPSLGRN ASAPPEPPRL  60
   61 AIGGGGQDNG RQHSPGERIS IIFTLRNQVG NLARALQVFQ ELGINVLHLE LSPLEMATNQ 120
  121 ADVLVDVECD QRRLDQVVKM LNREVASVNY TSVNTQGLAR APSLSACSSF DFGDMVWFPR 180
  181 KISDLDKAQN VLMYGSELDA DHPGFKDPVY RKRREQFSAI ANNFKHGNPI PRVQYTPEEV 240
  241 KTWGTVFLEL HRLYVLHAVP EYMDNWPELE KYCGYREDNV PQLQDVSVYL KRKTGFQLRP 300
  301 VAGYLSPRDF LSGLAFRVFH CTQYIRHSSD PFYTPEPDCC HELLGHMPLL ANSSFAQFSQ 360
  361 EIGLASLGAS DADIEKLATL YFFTVEFGLC KQADSTFKVY GAGLLSSVAE LQHAITAENK 420
  421 IKKFDPEVTC QQECIITSYQ NAYYYTDSFE EAKEQMRAFA ESIQRPFGVR YNPYTMSVEV 480
  481 LSNAKKITAV VSELRGDLSI VCSALRKISA TDENLDVDSI ANMLHNSLNV RGGASGGGGS 540
  541 PCSPDNSDNS TAEGD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.67

Protein Overview: Trh-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: