Protein Overview: hipk-PB, hipk-PA

General Information:
Name(s) found:	hipk-PA / FBpp0072451 [FlyBase] hipk-PB / FBpp0072450 [FlyBase]
Description(s) found: Found 30 descriptions. SHOW ALL	The gene homeodomain interacting protein kinase is referred to in FlyBase by the symbol Dmel\hipk (CG17090, FBgn0035142). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:543070..576065. It has the cytological map location 61C3-61C5. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: compound eye development; positive regulation of Notch signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; intersegmental nerve; eye photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene homeodomain interacting protein kinase is referred to in FlyBase by the symbol Dmel\hipk (CG17090, FBgn0035142). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:543070..576065. It has the cytological map location 61C3-61C5. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: compound eye development; positive regulation of Notch signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; intersegmental nerve; eye photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1340 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	protein amino acid phosphorylation [IEA][NAS] compound eye development [IMP] positive regulation of Notch signaling pathway [IGI]
Molecular Function:	ATP binding [IEA] protein kinase activity [NAS] protein serine/threonine kinase activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTSYPPKAS DFVDYAVAGG GGSGFCSGLG AGLSVRATSF YGDQTVTATT DGTRHQEQQQ  60
   61 QQLQQQQQQH ILRQPATSAS TSSVAAAATS KRKRQTDCDC GCVDSYNSSH GPPVQQDSSA 120
  121 AAGAGSVGSK AGSGPGPDGI GPISSLKTAH TKVATSGGHA NTQPPSKRSS SGADGDYQLV 180
  181 QHEVLYSLSA EYEVLEFLGR GTFGQVVKCW KRGTSEIVAI KILKNHPSYA RQGQIEVSIL 240
  241 SRLSQENADE FNFVRAFECF QHKNHTCLVF EMLEQNLYDF LKQNKFSPLP LKYIRPILEQ 300
  301 VLTALLKLKQ LGLIHADLKP ENIMLVDPVR QPYRVKVIDF GSASHVSKTV CNTYLQSRYY 360
  361 RAPEIILGLP FCEAIDMWSL GCVVAELFLG WPLYPGSSEF DQIRYISQTQ GLPTEHMLNS 420
  421 ASKTSKFFYR DVDSTYPFWR LKTTEEHEAE TNTKSKEARK YIFNCLDDIG QVNVPTDLEG 480
  481 GQLLAEKTDR REFIDLLKRM LTIDQERRLT PAEALNHSFT RLTHLVDYVY CNNVKASVQM 540
  541 MEVCRRGDFH TVQPASTLVT NFVPSSTENM TFTINNQLTS QVQRLVRDGR PLAYEGLYQI 600
  601 YNGRSVARQY PQTRTDSFQH QLVSNILCPP SYQTMPSPTK HVVVGSATMQ PPLQVPPQQY 660
  661 VNVPVPVSMV EPTSGQRMLL TNRVQASGVA WPQTGRQMAL VPSWPQQAPA HSLIVDSTPL 720
  721 FNVEEIYPKH HLNLPRNDLK KESPAHHIAK GNSYRVPRHE KKEHQQLSPV KKRVKESSPP 780
  781 HQQRYQRAAH VSPQYHAHHN CNYGNGSGYS ASAGSVVASS AASSSNIVNG SSSSSHHHHV 840
  841 PVAHAQPYSS SSGHHIVSNC NANGGAGGAV VYQQPPAHAH QQHGQQPHPQ SSQHPQHVKQ 900
  901 PTITIHDTPS PTAVITISDS EDEGGEAGGA QVPVLKQRAH AQSQTSGSLL QHAPSSSCSR 960
  961 SSAHQQPHPH PQQQQQQQIN YGDHDPEDAR RRHHAAAAAA VGSPKHHHHQ QQQQPAPPPQ1020
 1021 QQQQQYQPQP PPQQVLPQPQ PSIKYEPGQS QKKRILAMAQ SECGYQPQVP SQPSSSASLP1080
 1081 HIPTKQEPAE FYPEYAAAPP QQLDTKRSSW APTSSGSGVS ALPLAHPKRE APSVAPISYV1140
 1141 APSVAPPLAH SKSSSASSSS SISAATAAAA AAAAAAAASV GPPSWGPPQV YRQPSQPPPG1200
 1201 SVGLPGSTQP PPSSVAPHPH HHSHGHHHHQ AGTPLGGSPS STAAAALLQP DIYAQGDIYR1260
 1261 RPTVFVSQAA PSYAYANRAV VAPPPAHNSS SRQVIPSHPL PAHIQIPTQY SQFGPLSPAQ1320
 1321 VAASKHAAHF APTNIWYGAE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.27

Protein Overview: hipk-PB, hipk-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: