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Protein Overview: FBpp0310094, pio...

General Information:
Name(s) found: FBpp0310094 [FlyBase]
pio-PD / FBpp0290717 [FlyBase]
pio-PB / FBpp0072219 [FlyBase]
Description(s) found:
Found 37 descriptions.
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  • type=protein; loc=2R:join(20476278..20476328,20476900..20476948,20479475..20479697,20479756..20479822,20483381..20483862,20483919..20484237,20484291..20484488); ID=FBpp0310094; name=pio-PE; parent=FBgn0020521,FBtr0343486; dbxref=FlyBase:FBpp0310094,FlyBase_Annotation_IDs:CG3541-PE; MD5=7e4c0564a89968d580d00545c06fc636; length=462; release=r5.56; species=Dmel; [FlyBase]
  • The gene piopio is referred to in FlyBase by the symbol Dmel\pio (CG3541, FBgn0020521). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20468772..20485385. It has the cytological map location 60D7-60D8. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; chitin-based cuticle attachment to epithelium; open tracheal system development; chitin-based embryonic cuticle biosynthetic process. 13 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; embryonic/larval tracheal system; portion of tissue; tracheal system; anatomical structure; cuticle; integumentary system; lateral trunk posterior branch; adult trachea; embryonic tracheal system. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene piopio is referred to in FlyBase by the symbol Dmel\pio (CG3541, FBgn0020521). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20468772..20485385. It has the cytological map location 60D7-60D8. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; chitin-based cuticle attachment to epithelium; open tracheal system development; chitin-based embryonic cuticle biosynthetic process. 13 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; embryonic/larval tracheal system; portion of tissue; tracheal system; anatomical structure; cuticle; integumentary system; lateral trunk posterior branch; adult trachea; embryonic tracheal system. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 462 amino acids

    Gene Ontology:
    Cellular Component: apical part of cell [IDA]
    Biological Process: chitin-based cuticle attachment to epithelium [IMP]
    chitin-based embryonic cuticle biosynthetic process [IMP]
    apposition of dorsal and ventral imaginal disc-derived wing surfaces [IMP]
    open tracheal system development [IMP]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTGTRMDAF HTALHLITIA ALTTHAAQIP TAMKDAQSSL SDAIAAAEAE VASTSKPAVE  60
   61 PSVRIKCLSG SMLITIKDAP PNHETGLFSG MIYPKGLSKN STCLSEYRDH VGSLRYKLPL 120
  121 RSCNTMPKET DDGGIEFFNT IVLQPHLKLI TDLGRGYHVR CAYKSRDAAM KPKKYLRKHA 180
  181 QKPQAFRSDD RREYGRSLDK QQDDDLDEED VYDANAPTQE EDVTNNEIPM PGCHMKIYND 240
  241 EHKIADDVKI GDPLTIVISI DKQKVYGLHV TDCIVRDGLG WGEQRLVGED GCPMDNEIMG 300
  301 QFNYTQDRLA ANVTFPAHKF PYTTSVYYQC NVRLCALEDP TCQEAPQCSG KRPKRQAAAD 360
  361 SKEEDGLPAT IEVFSGLYVN ENENANDSDE DAVYKEKTLD DALCVSQRTF AIAIAIAGLI 420
  421 LMLAVVAAVL CIMARRSTKT VSNSGSSIYS GPYTNTAFSH SS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..358] FFAS03 0.952 Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi
    2 View Details [359..462] MSA 1.273995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.98284647203605 bayes_pls_golite062009
  • protein binding
    		•  1.13133758103628 bayes_pls_golite062009
  • receptor activity
    		•  0.213240821853848 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle