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Protein Overview: spag-PA

General Information:
Name(s) found: spag-PA / FBpp0072164 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene spaghetti is referred to in FlyBase by the symbol Dmel\spag (CG13570, FBgn0015544). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20046888..20049021. It has the cytological map location 60C1. There is experimental evidence that it has the molecular function</span>: chaperone binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc development; cell proliferation; imaginal disc fusion, thorax closure; imaginal disc growth. 8 alleles are reported. The phenotypes of these alleles are annotated with: trichome; lymph gland; wing; imaginal disc; melanotic mass. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 534 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cell proliferation [IMP]
    imaginal disc fusion, thorax closure [IMP]
    imaginal disc development [IMP]
    imaginal disc growth [IMP]
    Molecular Function: protein serine/threonine phosphatase activity [ISS]
    chaperone binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAQEKAFEL QRQVRQNARE YENSVKDLYS WEQDIKNKEK ELQKSPLSAA NKDLPVRSHV  60
   61 QTDKSRKESP SSSAASSPTE KQDLPVDPVA QQYKKANDIK DRGNTYVKQG EYEKAIVAYS 120
  121 TAIAVYPHDP IYHINRALCY LKQESFDQCV EDCEAAIALD KLCVKAYYRR MQANESLGNN 180
  181 MEALKDCTTV LAIEPKNIEA KRSLARINDR LRKIATKSGP NFTPDRPGMI EILPIEKPAY 240
  241 KRSKKAMRSV PVVDVVSPRA TIDDSNQLRI SDEDIDKIFN SNCGIIEEVK KTNPKPTPMP 300
  301 DTSGPPKAET IAKTSKEVKP TKQTAVKVAP AVETPKETET RKDTKIVPES DNEAKPSAPK 360
  361 KTAVEVPKVQ TQVSPPKTTI ERSPEVNTVQ TEKIEQASSN NAMSPSPIER FLPPAPTSTA 420
  421 QFHVTWKELS GPQKYQYLKS IEVPNLCKIL GAGFDSDTFA DLLRTIHDFF VPNKEPNTAA 480
  481 VLLEISKNDE FTILAMLMSA EEKKMVSSIL NAIKNWPSKN PAVLDNLFKE YGVA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..67] PSI-BLAST 8.154902 Transcription factor MalT domain III
    2 View Details [68..534] PSI-BLAST 56.0 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle