YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: alpha-catenin-re...

General Information:
Name(s) found: alpha-catenin-related-PA / FBpp0072057 [FlyBase]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • The gene alpha-catenin related is referred to in FlyBase by the symbol Dmel\alpha-catenin-related (CG2987, FBgn0029105). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19845630..19849148. It has the cytological map location 60A14. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cell adhesion. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 787 amino acids

    Gene Ontology:
    Cellular Component: zonula adherens [ISS]
    actin cytoskeleton [IEA]
    Biological Process: cell adhesion [IEA]
    Molecular Function: actin binding [ISS]
    structural molecule activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYGITQSTVN NQRFRVRDMD NEQIMSTFGN IGHLLNIAVE RFITIGEIIA EENIDIKGDM  60
   61 YEAAKEARDA GKSIERLCDI SPLSGMELRH HIEPLKDYGA IILAARSLLS SVTRILLLVD 120
  121 IIVVKKLLTA KKRASESLEK LESVMNFTEF VRAFSVFGTE MIELAYLTGH HRNSFKEERR 180
  181 RAQMFSARQI LEKSIAILLT SSKNSLIHSD CVIVKENRDT VFCQIRRAMD LIHFVVKDSI 240
  241 FDTAKHMPFE KQASNPNYEN ESIYTTIKRI VNLIKRYKYQ MSYYEGSGEG NNNSDAYFSF 300
  301 LDDDLWKSEK NLPSAAGGGR MVNNTNFRKH LSSESLDLRE ELSLAFEKLF EKAHDFTDSP 360
  361 YISHNHRKNI LSYCDNCKLE FDLYLNTIMK DQHEGGGGAG GVGGVGGGQV KGRSDPELGM 420
  421 LSSLEELCKQ LVVSVSSQIE DFNESLKICS KLVKSFHVLA TNYDIDNLNQ RSSKFHDCCD 480
  481 HIFDICKLLQ HIAPTERLQV QAKCLAINLR IYGPQVFIAA KILWKYSNSS AANENFESFS 540
  541 DMWKWLTNEI SMIAKKILVS INTTKGDRDA DAEKCESSSD KLTKSGVPAT EDGEMVEYSG 600
  601 LEGKNNGDLN TYQSKWSEDL SDDNDILKRA KNMSAMAFLM YQFTKGNGSL RTTQDLFTQA 660
  661 EYFAEEANRL YKVLRHFSYQ VPASDNKKDL LNILDRVPTF VQALQFTVKD HTVGKAATFV 720
  721 KVDHVIRETK NLMNVINKVV SKCFECATKY KLNLTGITGG LTSERSNENM AGGMCDSKGT 780
  781 TSSSDIP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..587] PSI-BLAST 34.0 Crystal structure of a cytoskeletal protein
    2 View Details [588..787] PSI-BLAST 12.221849 Human vinculin head (1-258) in complex with human vinculin tail (879-1066)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.47862012796505 bayes_pls_golite062009
  • protein binding
    		•  2.02579891050608 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.07751635463993 bayes_pls_golite062009
  • cadherin binding
    		•  0.801778192092067 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.47862012796505 bayes_pls_golite062009
  • protein binding
    		•  2.02579891050608 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.07751635463993 bayes_pls_golite062009
  • cadherin binding
    		•  0.801778192092067 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle