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Protein Overview: TBPH-PA

General Information:
Name(s) found: TBPH-PA / FBpp0088569 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene TBPH is referred to in FlyBase by the symbol Dmel\TBPH (CG10327, FBgn0025790). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19746590..19750135. It has the cytological map location 60A4-60A5. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: adult locomotory behavior; neuromuscular junction development. 8 alleles are reported. The phenotype of these alleles is annotated with: larval neuromuscular junction. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 332 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: neuromuscular junction development [IMP]
    adult locomotory behavior [IMP]
    Molecular Function: nucleotide binding [IEA]
    nucleic acid binding [IEA]
    mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFVQVSEEE GDEPIELPAE EDGTLLLSTL QAQFPGSCGL KYRNLDTKAV RGVRSNEGRL  60
   61 FPPSVESGWG EYAYFCVFPK ENKRKSDDNL ENSTAKTKRI ETRLRCTDLI VLGLPWKTTE 120
  121 ESLREYFETY GEVLMAQIKK DTKSGQSKGF GFVRFGSYDA QMRVLTNRHL IDGRWCEVKV 180
  181 PNSKGMGHQV PCKVFVGRCT EDINSDDLRE YFSKFGEVTD VFIPRPFRAF SFVTFLDPDV 240
  241 AQSLCGEDHI IKGVSVHVSN AAPKAEQNRN QQVQSYNYNS ANSFGMHSYH PQGNHMNPGR 300
  301 NGHHRGRQFS ILDGSERGPQ QCQQLWWTEG AE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A No confident structure predictions are available.
    2 View Details [102..262] PSI-BLAST 41.0 Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
    3 View Details [263..332] PSI-BLAST 11.69897 Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  2.96087565414382 bayes_pls_golite062009
  • binding
    		•  2.29041217255208 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.91189490017911 bayes_pls_golite062009
  • mRNA binding
    		•  1.52245536665132 bayes_pls_golite062009
  • protein binding
    		•  0.0101134374085809 bayes_pls_golite062009
    3
    Term Confidence Notes
  • RNA binding
    		•  2.96087565414382 bayes_pls_golite062009
  • binding
    		•  2.29041217255208 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.91189490017911 bayes_pls_golite062009
  • mRNA binding
    		•  1.52245536665132 bayes_pls_golite062009
  • protein binding
    		•  0.0101134374085809 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle