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Protein Overview: CG5554-PA

General Information:
Name(s) found: CG5554-PA / FBpp0072035 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5554 (CG5554, FBgn0034914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19732415..19734547. It has the cytological map location 60A3. Based on sequence similarity, it is predicted to have molecular function</span>: protein disulfide isomerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cell redox homeostasis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: cell redox homeostasis [IEA]
    Molecular Function: protein disulfide isomerase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSTSYFVAA TCAALLLLAA TAQSTAAAQS GLQPGGKLIE LDEDNWHLML QGEWMIEFFA  60
   61 PWCPACKNLA PTWERFARVA KDVQVQVAKI DVTTSPSLSG RFFVTALPTI YHVKDGEFRQ 120
  121 YRGARDGDAL LYFVKKQQWQ SIEPLSAWKK PDTTHMSVLS YFFKLSHTLK DFNGRLQEEY 180
  181 GLPTWGSYAL FAIATIFVGA ALGLLLVCLV DFVYPPKKSQ RQSFSESQDN LTEGLEDLAT 240
  241 EEIEDDGDAE ENDDEQRDSD EEEQEDDDEE EEDSEEQVGD LATKEKEADS EPEKEEKPEP 300
  301 KQAGDAAPEK TEQVRKRKPR KGD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 31.69897 The solution structure of the thioredoxin-like domain of human Thioredoxin-related transmembrane protein
    2 View Details [153..323] PSI-BLAST 6.522879 HUMAN PROTEIN DISULFIDE ISOMERASE, NMR, 24 STRUCTURES


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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