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Protein Overview: Fib-PA

General Information:
Name(s) found: Fib-PA / FBpp0071892 [FlyBase]
Description(s) found:
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  • gi|7291525|gb|AAF46950.1| fibrillarin [Drosophila melanogaster] [NCBI NR]
  • gi|55584008|sp|Q9W1V3.1|FBRL_DROME RecName: Full=rRNA 2'-O-methyltransferase fibrillarin [NCBI NR]
  • gi|17647425|ref|NP_523817.1| fibrillarin [Drosophila melanogaster] [NCBI NR]
  • rRNA 2'-O-methyltransferase fibrillarin OS=Drosophila melanogaster GN=Fib PE=2 SV=1 [Swiss-Prot]
  • The gene Fibrillarin is referred to in FlyBase by the symbol Dmel\Fib (CG9888, FBgn0003062). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18960414..18962243. It has the cytological map location 59C3. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: rRNA processing; RNA processing. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG9888-PA translation from_gene[CG9888 Fib FBgn0003062] seq_release:3 mol_weight=34638 cds_boundaries:(2R:18,116,632..18,118,162[-]) aa_length:344 transcript_info:[CG9888-RA seq_release:3] gene_info:[gene symbol:Fib FBgn0003062 gene_boundaries:(2R:18, [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W1V3) FIB protein [DrosMelano7227.FASTAC.txt]
  • (AE003459) Fib gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG9888-PA [Drosophila melanogaster]gi|17647425|ref|NP_523817.1| CG9888-PA [Drosophila melanogaster]gi|55584008|sp|Q9W1V3|FBRL_DROME Fibrillarin [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(18960584..18961165,18961547..18961986,18962105..18962117); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_p [fly-100309-contam.fasta]
  • CG9888-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • rRNA 2'-O-methyltransferase fibrillarin [nr-271106-contam.fasta]
  • Fibrillarin CG9888-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(18960584..18961165,18961547..18961986,18962105..18962117); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_protein:AAF46950; MD5=19665765e4e9749a82627001f88e480a; length=344; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(18960584..18961165,18961547..18961986,18962105..18962117); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_protein:AAF46950; MD5=19665765e4e9749a82627001f88e480a; length=344; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • rRNA 2'-O-methyltransferase fibrillarin OS=Drosophila melanogaster GN=Fib PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • GM13963p OS=Drosophila melanogaster GN=Fib-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(18960584..18961165,18961547..18961986,18962105..18962117); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_protein:AAF46950,FlyMine:FBpp0071892,modMine:FBpp0071892; MD5=19665765e4e9749a82627001f88e480a; length=344; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(23074582..23074594,23074024..23074463,23073061..23073642)); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_protein:AAF46950,FlyMine:FBpp0071892,modMine:FBpp0071892; MD5=19665765e4e9749a82627001f88e480a; length=344; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(23074582..23074594,23074024..23074463,23073061..23073642)); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_protein:AAF46950,FlyMine:FBpp0071892,modMine:FBpp0071892; MD5=19665765e4e9749a82627001f88e480a; length=344; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0071892 type=protein; loc=2R:complement(join(23074582..23074594,23074024..23074463,23073061..23073642)); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_protein:AAF46950,FlyMine:FBpp0071892,modMine:FBpp0071892; MD5=19665765e4e9749a82627001f88e480a; length=344; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(23074582..23074594,23074024..23074463,23073061..23073642)); ID=FBpp0071892; name=Fib-PA; parent=FBgn0003062,FBtr0071982; dbxref=FlyBase:FBpp0071892,FlyBase_Annotation_IDs:CG9888-PA,GB_protein:AAF46950.1,REFSEQ:NP_523817,GB_protein:AAF46950,UniProt/Swiss-Prot:Q9W1V3,FlyMine:FBpp0071892,modMine:FBpp0071892; MD5=19665765e4e9749a82627001f88e480a; length=344; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 344 amino acids

    Gene Ontology:
    Cellular Component: Cajal body [IDA]
    small nuclear ribonucleoprotein complex [ISS]
    nucleolus [IDA]
    small nucleolar ribonucleoprotein complex [ISS]
    dense fibrillar component [ISS]
    Biological Process: tRNA processing [IEA]
    RNA processing [ISS]
    rRNA processing [ISS]
    Molecular Function: mRNA binding [ISS]
    methyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKPGFSPRG GGGGGGGGGG GFRGRGGGGG GGGGGFGGGR GRGGGGDRGG RGGFGGGRGG  60
   61 GGRGGGGGGG RGAFGGRGGG GGRGGGGRGG GGRGGGGRGG GAGGFKGGKT VTIEPHRHEG 120
  121 VFIARGKEDA LVTRNFVPGS EVYGEKRISV ETNGEKIEYR VWNPFRSKLA AAVLGGVEQI 180
  181 HMPPGSKVLY LGAASGTTVS HVSDVVGPEG LVYAVEFSHR SGRDLINVAK KRTNIIPIIE 240
  241 DARHPHKYRM LVGMVDTIFA DVAQPDQGRI VALNAQHFLK NGGHFVISIK ASCIDSTAQP 300
  301 EAVFAAEVKK MQADKLKPQE QLTLEPYERD HAVVVGVYRP PPKQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] FFAS03 2.58 Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
    2 View Details [103..344] PSI-BLAST 118.0 No description for 2ipxA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle