YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: dnr1-PA

General Information:
Name(s) found: dnr1-PA / FBpp0071748 [FlyBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • The gene defense repressor 1 is referred to in FlyBase by the symbol Dmel\dnr1 (CG12489, FBgn0260866). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18451012..18480473. It has the cytological map location 58E9-58F1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; immune response. 19 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 676 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEA]
    Biological Process: immune response [IMP]
    negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWCIVNLPNG TQQAVKWDPK ANGQECLEKV CRAMNIICEM EYFGLEHWTP NQKESQTRQW  60
   61 INLRNRLSGD SGSSGSGIQL MLALRVKFWV PVHFILQESV RNLFYMQARR DLLEGRLTAP 120
  121 DWSGAAKLAA LLCQADGLRF NESSLKADCP MRMRRELAQQ QQQQQQQAQQ HRLEQQRKEK 180
  181 EHVLSFKKRR LSKQKSMEHI EVCTLPAAST TSCSLQPSPS ASASASASAS ASASASTSAC 240
  241 SQTHSNSSSS SPSNSSSQTG LDERLASNPL RVYEEYFMQP SCEGEPPADY LRQIAVEHGK 300
  301 LAKLQMSLKT AKYWLLKSIQ DLEGYGEELF SGVTTNESAT RCDIAVGAHG ITVCRGGEKQ 360
  361 SIPFGAIAAA KSLRRTFKLE YVDDHNDRKE LEIKLPKQPI AAGLYRSITE RHAFYVCDKV 420
  421 RGVVTNQFTR DLKGTIASMF MENTELGKRY VFDIQHTCRE VHDQARRTLH ERGGDLVAEG 480
  481 AEGCSAVAGG LGASAVGEPG VSPWAMALTT GAGGSMAGKI DLAIREKEAR EAAIERCVDT 540
  541 RISEAMQCKI CMDRAINTVF NPCCHVIACA QCAARCSNCP NCRVKITSVV KIYLPPELRT 600
  601 SQTGSGATTT SSSSIMGDGQ VEEQLLQQQL DEISAAPASL EAGADAGVGV GGMAVGAGAG 660
  661 AGATGPGGQP KVTTAA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..328] PSI-BLAST 72.69897 Radixin
    2 View Details [329..416] FFAS03 2.95 No description for 2he7A was found.
    3 View Details [417..676] PSI-BLAST 9.0 Cbl; N-terminal domain of cbl (N-cbl); CBL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.0934358341245259 bayes_pls_golite062009
  • protein binding
    		•  0.03789551947602 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.434026084000615 bayes_pls_golite062009
  • protein binding
    		•  0.31534665043077 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle