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Protein Overview: Oatp58Dc-PB, Oat...

General Information:
Name(s) found: Oatp58Dc-PC / FBpp0290691 [FlyBase]
Oatp58Dc-PB / FBpp0112018 [FlyBase]
Oatp58Dc-PA / FBpp0071690 [FlyBase]
Description(s) found:
Found 39 descriptions.
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  • The gene Organic anion transporting polypeptide 58Dc is referred to in FlyBase by the symbol Dmel\Oatp58Dc (CG3380, FBgn0034716). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18111186..18116073. It has the cytological map location 58D2. Based on sequence similarity, it is predicted to have molecular function</span>: sodium-independent organic anion transmembrane transporter activity; organic anion transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: organic anion transport. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Organic anion transporting polypeptide 58Dc is referred to in FlyBase by the symbol Dmel\Oatp58Dc (CG3380, FBgn0034716). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18111186..18116073. It has the cytological map location 58D2. Based on sequence similarity, it is predicted to have molecular function</span>: sodium-independent organic anion transmembrane transporter activity; organic anion transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: organic anion transport. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Organic anion transporting polypeptide 58Dc is referred to in FlyBase by the symbol Dmel\Oatp58Dc (CG3380, FBgn0034716). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18111186..18116073. It has the cytological map location 58D2. Based on sequence similarity, it is predicted to have molecular function</span>: sodium-independent organic anion transmembrane transporter activity; organic anion transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: organic anion transport. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 789 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: organic anion transport [ISS]
    Molecular Function: organic anion transmembrane transporter activity [ISS]
    sodium-independent organic anion transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQSENPSSL GAELQDLEHG RRESRDESDV ESRLLNNGKS YDKEKEAGNQ DGEETTPKTG  60
   61 KSKKKKQKSE QDRLMTAEIN KLLAESPLEK NVTCGFWIFK GTFYQRFANQ TAYVLLYGIV 120
  121 GCIFSMTYAY FNGTITTIEK RFKIPSKNTG IISVGNDISQ TLVSAVLAYY AGKGHRPRWI 180
  181 GFGLLTIVFF CILTTAPHFL YGPGEDALAL TSEFGGMPDE NATMEAIEEQ RSKTLCRLNG 240
  241 GGAECEVGEG NFAPQLLLFV AQFISGIGGS LYYTLGVSYM DDNTKKSKTP ALLSLSYFLR 300
  301 MLGPAIGYAL ASFCLRLYIA PQMHPVINNK DPRWLGAWWL GWLVMGGLLS FSGVFLSMFP 360
  361 KELPRAVARR KVEENRRREK ERLSVKSTEK ERLTAELDQK TTAEAKASFQ DMLKTFRRLI 420
  421 TNKTYMCNTL SSIFYLVGYT PYWIFTPKYI EVQYRQSAAT SSMVTGTVAL AFSAVGVLLS 480
  481 GFIISRYKPR ARYMAAWNVI VGFLTVAGIL AYAFIGCPGN ESSVIVNIHD SSLAGNTTTC 540
  541 NSACSCDYVR YSPVCGENNM TYISACHAGC KKLLVNSEGK KIFYDCSCIP SDDAGNSTSQ 600
  601 FKRLTSFDLS NDEVSQNTSV HSQLEALANG QAMPGACPVN CWTQFVAFLA VMCCLKFVGA 660
  661 SGRASNFLVS VRCVPEKDKT AAMGFGMTLC SMLAFIPSPI FFGWVFDRVC LVWGKTCTNK 720
  721 GNCWLYDPLS MRYTLNFTAA VFIAIGAIFD LGVWYYAKDL KIFDEDVKEV EMKIVQHEEE 780
  781 ANNEKNTEI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..143] deduced N/A No confident structure predictions are available.
    2 View Details [144..586] PSI-BLAST 11.221849 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
    3 View Details [587..789] FFAS03 1.21 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.88180006470231 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  3.3413526350788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.05701989682533 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  0.312628600969375 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle