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Protein Overview: FBpp0309730, Ppc...

General Information:
Name(s) found: FBpp0309730 [FlyBase]
Ppcdc-PA / FBpp0071589 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=2R:join(17579501..17579675,17579740..17579879,17579937..17580197); ID=FBpp0309730; name=Ppcdc-PB; parent=FBgn0050290,FBtr0342959; dbxref=FlyBase:FBpp0309730,FlyBase_Annotation_IDs:CG30290-PB; MD5=99a4a734c5a23eacf358e8131dc2065e; length=191; release=r5.56; species=Dmel; [FlyBase]
  • The gene Phosphopantothenoylcysteine decarboxylase is referred to in FlyBase by the symbol Dmel\Ppcdc (CG30290, FBgn0050290). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17579095..17580269. It has the cytological map location 57F8-57F9. Based on sequence similarity, it is predicted to have molecular function</span>: phosphopantothenoylcysteine decarboxylase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: coenzyme A biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 191 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: coenzyme A biosynthetic process [UNKNOWN]
    Molecular Function: phosphopantothenoylcysteine decarboxylase activity [UNKNOWN]
    catalytic activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPERNVMIA ATGSVATIKL AQLIRELSDE RLPFKFHLKV LITEAAKHFF ELEQIPENVP  60
   61 IYHNRDEWIT WNKRGDPVLH IDLGKWADLL VIAPLSANSL SKMATGICDN IVMCVVRAWD 120
  121 LEKPLLFAPA MNTRMYDHPI TREQIDKLTS WGYKEIPCIS KTLMCGDTGN GAMAEVPTIV 180
  181 EAVLSAFQPI K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..191] PSI-BLAST 54.69897 4'-phosphopantothenoylcysteine decarboxylase (PPC decarboxylase, halotolerance protein Hal3a)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphopantothenoylcysteine decarboxylase activity
    		•  3.86093811191169 bayes_pls_golite062009
  • phosphopantothenate--cysteine ligase activity
    		•  2.64345867885176 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.79168084682693 bayes_pls_golite062009
  • catalytic activity
    		•  1.51672397362026 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.03827559540394 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.47

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle