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Protein Overview: Sdc-PA

General Information:
Name(s) found: Sdc-PA / FBpp0071623 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • The gene Syndecan is referred to in FlyBase by the symbol Dmel\Sdc (CG10497, FBgn0010415). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17281122..17368680. It has the cytological map location 57E1-57E6. Based on sequence similarity, it is predicted to have molecular function</span>: transmembrane receptor activity. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance; detection of light stimulus involved in visual perception; axon guidance. 50 alleles are reported. The phenotypes of these alleles are annotated with: medulla; muscle fiber; embryonic central nervous system; abdominal segmental nerve; lamina plexus; lateral transverse muscle. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 399 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    extracellular region [NAS]
    plasma membrane [ISS][NAS]
    Biological Process: detection of light stimulus involved in visual perception [IMP]
    motor axon guidance [IMP]
    axon guidance [IMP]
    Molecular Function: transmembrane receptor activity [ISS]
    cytoskeletal protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPKQKISVE PLLLVAILIG VLVAATHAQD QKSVKPSAAA PSAAASRPHD EIYIDDDSIE  60
   61 GSGGRGGIHE DLEKDPDYSG SGFGPDDEDA EPDQHSHSSH NTRISQSSNS GINTAHTPTQ 120
  121 TSSTIPTTST STPMPTTTPT ATTPASTTTA AATQISSFAN SSSTTTTTLA PTIPAEPQQP 180
  181 LFPPFDKDLD TESSGDGIDA DAEDDDEDDG DDKDYDYNKE LDKEIDIDGP EPGHLPPVVH 240
  241 HNTVETGHIP TTDEIDVDGG DEDDNGDSDI DGPRIGGNDG DITERGPGAG GSNVHELDPN 300
  301 TNVNSQPSDT KGIDHRPNGN EVVIMSEDDR TSSFFSQPGI LAAVIGGAVV GLLCAILVVM 360
  361 FIVYRMRKKD EGSYALDEPK RSPANNSYAK NANNREFYA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] deduced N/A No confident structure predictions are available.
    2 View Details [81..205] MSA 1.145997 View MSA. No confident structure predictions are available.
    3 View Details [206..399] MSA 12.149992 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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