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Protein Overview: Acox57D-p-PA, FB...

General Information:
Name(s) found: FBpp0309692 [FlyBase]
Acox57D-p-PA / FBpp0071532 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=2R:join(17274187..17274328,17274420..17274582,17274647..17274939,17275003..17275408,17275470..17276082,17276156..17276311,17276376..17276636); ID=FBpp0309692; name=Acox57D-p-PB; parent=FBgn0034628,FBtr0342891; dbxref=FlyBase:FBpp0309692,FlyBase_Annotation_IDs:CG9707-PB; MD5=074d878da133a5d1c54a40b63d7d2563; length=677; release=r5.56; species=Dmel; [FlyBase]
  • The gene acyl-Coenzyme A oxidase at 57D proximal is referred to in FlyBase by the symbol Dmel\Acox57D-p (CG9707, FBgn0034628). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17273859..17276788. It has the cytological map location 57E1. Based on sequence similarity, it is predicted to have molecular function</span>: acyl-CoA oxidase activity; palmitoyl-CoA oxidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; fatty acid beta-oxidation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 677 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [ISS]
    Biological Process: fatty acid beta-oxidation [IEA]
    oxidation reduction [IEA]
    Molecular Function: acyl-CoA dehydrogenase activity [IEA]
    acyl-CoA oxidase activity [ISS]
    FAD binding [IEA]
    palmitoyl-CoA oxidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSTSVIPT TVNPDLQKER DAASFNSEEF AAWWAGGEEV LKFNRGVREY MEKDVDLSEM  60
   61 LQLQNKTHEE IIEFSTRGAI EGAKKLRRLQ EERNPGGDVY WPNLYDAQVM WGLVPGGNPF 120
  121 GVMYVMLVKA LQAQCTPEQY EEFGKRVELF EICGTYAQTE LGHGTYLRGL ETRADFDRKT 180
  181 DQFVLNTPNI SSYKWWPGGL GHSSNHCLVM AQLYIDGDCK GPHMFFIQVR DEDTHEPLPG 240
  241 VHIGDIGKKM GFIGVNNGFL GLKNVRIPRT RMLMRHAQVK ADGSYVSSPT NVLTYFAMVR 300
  301 TRCVIAKNNA VMLASAATIA TRYSAVRRQS PINPNEREPQ IMDHVTQQMK LFPEIATSVA 360
  361 YRKAGDYLWN LYDVTIEDIE NGKYERLPEL HSLSCALKVT CSMDSASGVE KLRLACGGHG 420
  421 FLTSSNMSSI YVSATAACTY EGENTVLLLQ IGRFLMKTWR AALTGAPLPP TVRYLAEVQK 480
  481 NPEFGTWTGS WENMVKAMQY AAANRTQLAF RSLSKRMSRG ETEANAANHT GIEFTQAAEL 540
  541 HGRAFVFSAF YEAVTGPQSK TRSANFNRVL ENLLELYLVK ETLNQMGHLL RFINLTDTDL 600
  601 SGLQDRLETV LTKLRPDAVA IVDGFDFSDL QLNSTLGSYD GNAYERIFDA ALKNPMNQKA 660
  661 VPKYFHEILR PFMKSNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..677] PSI-BLAST 165.0 Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acyl-CoA oxidase activity
    		•  7.85164875699474 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  7.69964776555327 bayes_pls_golite062009
  • acyl-CoA dehydrogenase activity
    		•  6.0252876667118 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
    		•  5.50948952617422 bayes_pls_golite062009
  • palmitoyl-CoA oxidase activity
    		•  5.41720462605663 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.99827953439804 bayes_pls_golite062009
  • catalytic activity
    		•  2.41506805547596 bayes_pls_golite062009
  • pristanoyl-CoA oxidase activity
    		•  2.26651221125135 bayes_pls_golite062009
  • long-chain-acyl-CoA dehydrogenase activity
    		•  0.13696326544237 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle