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Protein Overview: CG8517-PA

General Information:
Name(s) found: CG8517-PA / FBpp0085636 [FlyBase]
Description(s) found:
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  • gi|28573567|ref|NP_611446.3| CG8517 [Drosophila melanogaster] [NCBI NR]
  • gi|28380711|gb|AAF57518.2| CG8517 [Drosophila melanogaster] [NCBI NR]
  • gi|17944731|gb|AAL48433.1| AT22380p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8517 (CG8517, FBgn0034472). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15601581..15602373. It has the cytological map location 56E2. Based on sequence similarity, it is predicted to have molecular function</span>: disulfide oxidoreductase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8517-PA translation from_gene[CG8517 CG8517 FBgn0034472] seq_release:3 mol_weight=16546 cds_boundaries:(2R:14,777,894..14,778,389[+]) aa_length:145 transcript_info:[CG8517-RA seq_release:3] gene_info:[gene symbol:CG8517 FBgn0034472 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V8Y6) CG8517-PA (AT22380p) [DrosMelano7227.FASTAC.txt]
  • CG8517-PA [Drosophila melanogaster]gi|17944731|gb|AAL48433.1| AT22380p [Drosophila melanogaster]gi|28573567|ref|NP_611446.3| CG8517-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(15601679..15601851,15601913..15602177); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518; MD5=7 [fly-100309-contam.fasta]
  • CG8517-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • AT22380p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(15601679..15601851,15601913..15602177); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518; MD5=76839236f6035ea400b6a5c35db0d1ee; length=145; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(15601679..15601851,15601913..15602177); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518; MD5=76839236f6035ea400b6a5c35db0d1ee; length=145; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • AT22380p OS=Drosophila melanogaster GN=CG8517 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(15601679..15601851,15601913..15602177); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518,FlyMine:FBpp0085636,modMine:FBpp0085636; MD5=76839236f6035ea400b6a5c35db0d1ee; length=145; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(19714174..19714346,19714408..19714672); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518,FlyMine:FBpp0085636,modMine:FBpp0085636; MD5=76839236f6035ea400b6a5c35db0d1ee; length=145; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(19714174..19714346,19714408..19714672); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518,FlyMine:FBpp0085636,modMine:FBpp0085636; MD5=76839236f6035ea400b6a5c35db0d1ee; length=145; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0085636 type=protein; loc=2R:join(19714174..19714346,19714408..19714672); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518,FlyMine:FBpp0085636,modMine:FBpp0085636; MD5=76839236f6035ea400b6a5c35db0d1ee; length=145; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(19714174..19714346,19714408..19714672); ID=FBpp0085636; name=CG8517-PA; parent=FBgn0034472,FBtr0086329; dbxref=FlyBase:FBpp0085636,FlyBase_Annotation_IDs:CG8517-PA,GB_protein:AAF57518.2,REFSEQ:NP_611446,GB_protein:AAF57518,UniProt/TrEMBL:Q7K037,FlyMine:FBpp0085636,modMine:FBpp0085636; MD5=76839236f6035ea400b6a5c35db0d1ee; length=145; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 145 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISS]
    Biological Process: cell redox homeostasis [IEA]
    response to DNA damage stimulus [IMP]
    Molecular Function: disulfide oxidoreductase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSYRRLFRA KRLMNLMKAN RGMTSTGKQP IFDVETRKDF EQRVINSDRP VVVDFHASWC  60
   61 CPCKALAPRL ENVVSEQEGR VRLARVDIDE HGELALDYNV GSVPSLVVIS NGKVVNRMVG 120
  121 LQTSEYLRKW LHKAVPHPPP EDTEN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] PSI-BLAST 28.69897 structure of human thioredoxin 2


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
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