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Protein Overview: SdhA-PA, SdhA-PC...

General Information:
Name(s) found: SdhA-PC / FBpp0085738 [FlyBase]
SdhA-PA / FBpp0085737 [FlyBase]
SdhA-PB / FBpp0085736 [FlyBase]
Description(s) found:
Found 50 descriptions.
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  • The gene Succinate dehydrogenase A is referred to in FlyBase by the symbol Dmel\SdhA (CG17246, FBgn0261439). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15279361..15283453. It has the cytological map location 56D3. Based on sequence similarity, it is predicted to have molecular function</span>: succinate dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: tricarboxylic acid cycle. 14 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Succinate dehydrogenase A is referred to in FlyBase by the symbol Dmel\SdhA (CG17246, FBgn0261439). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15279361..15283453. It has the cytological map location 56D3. Based on sequence similarity, it is predicted to have molecular function</span>: succinate dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: tricarboxylic acid cycle. 14 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Succinate dehydrogenase A is referred to in FlyBase by the symbol Dmel\SdhA (CG17246, FBgn0261439). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15279361..15283453. It has the cytological map location 56D3. Based on sequence similarity, it is predicted to have molecular function</span>: succinate dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: tricarboxylic acid cycle. 14 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 661 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex II [ISS][NAS]
    Biological Process: tricarboxylic acid cycle [ISS][NAS]
    electron transport chain [IEA]
    Molecular Function: succinate-CoA ligase (GDP-forming) activity [NAS]
    succinate dehydrogenase (ubiquinone) activity [ISS][NAS]
    FAD binding [IEA]
    electron carrier activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIMRVPSI LAKNAVASMQ RAAAVGVQRS YHITHGRQQA SAANPDKISK QYPVVDHAYD  60
   61 AIVVGAGGAG LRAAFGLVAE GFRTAVITKL FPTRSHTIAA QGGINAALGN MEEDDWKWHM 120
  121 YDTVKGSDWL GDQDAIHYMT REAPKAVIEL ENYGMPFSRT QDGKIYQRAF GGQSLKFGKG 180
  181 GQAHRCCAVA DRTGHSLLHT LYGQSLSYDC NYFVEYFALD LIFEDGECRG VLALNLEDGT 240
  241 LHRFRAKNTV IATGGYGRAF FSCTSAHTCT GDGTAMVARQ GLPSQDLEFV QFHPTGIYGA 300
  301 GCLITEGCRG EGGYLINGNG ERFMERYAPV AKDLASRDVV SRSMTIEIME GRGAGPEKDH 360
  361 VYLQLHHLPP KQLAERLPGI SETAMIFAGV DVTREPIPVL PTVHYNMGGV PTNYRGQVIT 420
  421 IDKDGKDVIV PGLYAAGEAA SSSVHGANRL GANSLLDLVV FGRACAKTIA ELNKPGAPAP 480
  481 TLKENAGEAS VANLDKLRHA NGQITTADLR LKMQKTMQHH AAVFRDGPIL QDGVNKMKEI 540
  541 YKQFKDIKVV DRSLIWNSDL VETLELQNLL ANAQMTIVSA EARKESRGAH AREDFKVRED 600
  601 EYDFSKPLDG QQKKPMDQHW RKHTLSWVCN DNGDITLDYR NVIDTTLDNE VSTVPPAIRS 660
  661 Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..661] PSI-BLAST 157.0 Avian respiratory complex ii with oxaloacetate and ubiquinone


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle