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Protein Overview: Jheh1-PA

General Information:
Name(s) found: Jheh1-PA / FBpp0085807 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Juvenile hormone epoxide hydrolase 1 is referred to in FlyBase by the symbol Dmel\Jheh1 (CG15101, FBgn0010053). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14740939..14742614. It has the cytological map location 55F7-55F8. There is experimental evidence that it has the molecular function</span>: juvenile hormone epoxide hydrolase activity. There is experimental evidence that it is involved in the biological process</span>: juvenile hormone catabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 474 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    Biological Process: juvenile hormone catabolic process [IDA][NAS]
    response to toxin [IEA]
    Molecular Function: juvenile hormone epoxide hydrolase activity [IDA][NAS]
    epoxide hydrolase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVTVKILVL ILAIAGGLVY RNVTQLWADL PAPKLDPQEW WGDEAQPKDY EAYLKNNSEV  60
   61 IGNRLSYPDK TIADLKERLN RTLRLTPPLE GVAFEYGFNT NYLKEVVEYW RDDYLPRWRE 120
  121 REVFLWQFNH FTTDIQGLRT HFLHLMVYDD NKVGKKHYPV LLLHGWPGSV REFYDFIHLL 180
  181 HQTNLDNNNK YIFNVVVPSL PGYGWSQGTS RKGLGPAQVA VMMRNLMLRL GYNKFFIQGG 240
  241 DWGSIIGSNI ATLYPENVLG YHSNMCNNLS PKSLAKGLVA EFWPSLFVPS GFEDFFFPKS 300
  301 NEMRYLMEES GYFHIQATKP DTIGAALTDN PVGLAAYILE KFSTWTNPSY RSLPDGGLTK 360
  361 RYKMDALLDN LMIYYLTNSI TTSQRLYAEQ YAQAQRDLHL DRVPTRVPTG CARFKSDIMQ 420
  421 FLDVQLKDKY TNLVHSTYHK KGGHFAALEV PKVLYKDFID FVETVERKFK IKTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..474] PSI-BLAST 48.522879 Bacterial epoxide hydrolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • juvenile hormone epoxide hydrolase activity
    		•  5.69212503305375 bayes_pls_golite062009
  • epoxide hydrolase activity
    		•  4.54228071084398 bayes_pls_golite062009
  • ether hydrolase activity
    		•  3.98161932704074 bayes_pls_golite062009
  • hydrolase activity, acting on ether bonds
    		•  3.22022434415297 bayes_pls_golite062009
  • hydrolase activity
    		•  1.75934962198703 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • lipase activity
    		•  1.27368159234978 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.11361651037277 bayes_pls_golite062009
  • carboxylesterase activity
    		•  0.424330502936163 bayes_pls_golite062009
  • binding
    		•  0.140475020321353 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  0.0576406065496096 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  0.00330927487011978 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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