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Protein Overview: FBpp0311723, Hs3...

General Information:
Name(s) found: FBpp0311723 [FlyBase]
Hs3st-A-PA / FBpp0085791 [FlyBase]
Description(s) found:
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  • gi|28573557|ref|NP_788409.1| heparan sulfate 3-O sulfotransferase-A [Drosophila melanogaster] [NCBI NR]
  • gi|28380728|gb|AAF57644.2| heparan sulfate 3-O sulfotransferase-A [Drosophila melanogaster] [NCBI NR]
  • gi|21464300|gb|AAM51953.1| GH20068p [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=2R:join(14633422..14633741,14635556..14635967,14636231..14636446,14638308..14638759,14639144..14639337,14639458..14639681); ID=FBpp0311723; name=Hs3st-A-PB; parent=FBgn0053147,FBtr0345672; dbxref=FlyBase:FBpp0311723,FlyBase_Annotation_IDs:CG33147-PB; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r5.56; species=Dmel; [FlyBase]
  • The gene Heparan sulfate 3-O sulfotransferase-A is referred to in FlyBase by the symbol Dmel\Hs3st-A (CG33147, FBgn0053147). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14605634..14642026. It has the cytological map location 55E9-55F1. Based on sequence similarity, it is predicted to have molecular function</span>: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG33147-PA translation from_gene[CG33147 CG33147 FBgn0053147] seq_release:3 mol_weight=66439 cds_boundaries:(2R:13,809,637..13,815,893[+]) aa_length:605 transcript_info:[CG33147-RA seq_release:3] gene_info:[gene symbol:CG33147 synonyms:[CG15074 CG1507 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8MRE7) GH20068p (CG33147-PA) [DrosMelano7227.FASTAC.txt]
  • CG33147-PA [Drosophila melanogaster]gi|21464300|gb|AAM51953.1| GH20068p [Drosophila melanogaster]gi|28573557|ref|NP_788409.1| CG33147-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(14633422..14633741,14635556..14635967,14636231..14636446,14638308..14638759,14639144..14639337,14639458..14639681); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_ID [fly-100309-contam.fasta]
  • CG33147-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH20068p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(14633422..14633741,14635556..14635967,14636231..14636446,14638308..14638759,14639144..14639337,14639458..14639681); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_IDs:CG33147-PA,GB_protein:AAF57644.2,REFSEQ:NP_788409,GB_protein:AAF57644; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(14633422..14633741,14635556..14635967,14636231..14636446,14638308..14638759,14639144..14639337,14639458..14639681); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_IDs:CG33147-PA,GB_protein:AAF57644.2,REFSEQ:NP_788409,GB_protein:AAF57644; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GH20068p OS=Drosophila melanogaster GN=Hs3st-A PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(14633422..14633741,14635556..14635967,14636231..14636446,14638308..14638759,14639144..14639337,14639458..14639681); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_IDs:CG33147-PA,GB_protein:AAF57644.2,REFSEQ:NP_788409,GB_protein:AAF57644,FlyMine:FBpp0085791,modMine:FBpp0085791; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_IDs:CG33147-PA,GB_protein:AAF57644.2,REFSEQ:NP_788409,GB_protein:AAF57644,FlyMine:FBpp0085791,modMine:FBpp0085791; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0311723; name=Hs3st-A-PB; parent=FBgn0053147,FBtr0345672; dbxref=FlyBase:FBpp0311723,FlyBase_Annotation_IDs:CG33147-PB,GB_protein:AHN56384,REFSEQ:NP_001286589; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_IDs:CG33147-PA,GB_protein:AAF57644.2,REFSEQ:NP_788409,GB_protein:AAF57644,FlyMine:FBpp0085791,modMine:FBpp0085791; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0311723; name=Hs3st-A-PB; parent=FBgn0053147,FBtr0345672; dbxref=FlyBase:FBpp0311723,FlyBase_Annotation_IDs:CG33147-PB,GB_protein:AHN56384,REFSEQ:NP_001286589; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0085791 type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_IDs:CG33147-PA,GB_protein:AAF57644.2,REFSEQ:NP_788409,GB_protein:AAF57644,FlyMine:FBpp0085791,modMine:FBpp0085791; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0311723 type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0311723; name=Hs3st-A-PB; parent=FBgn0053147,FBtr0345672; dbxref=FlyBase:FBpp0311723,FlyBase_Annotation_IDs:CG33147-PB,GB_protein:AHN56384,REFSEQ:NP_001286589; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0085791; name=Hs3st-A-PA; parent=FBgn0053147,FBtr0086608; dbxref=FlyBase:FBpp0085791,FlyBase_Annotation_IDs:CG33147-PA,GB_protein:AAF57644.2,REFSEQ:NP_788409,GB_protein:AAF57644,UniProt/TrEMBL:Q8MRE7,FlyMine:FBpp0085791,modMine:FBpp0085791; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2R:join(18745917..18746236,18748051..18748462,18748726..18748941,18750803..18751254,18751639..18751832,18751953..18752176); ID=FBpp0311723; name=Hs3st-A-PB; parent=FBgn0053147,FBtr0345672; dbxref=FlyBase:FBpp0311723,FlyBase_Annotation_IDs:CG33147-PB,GB_protein:AHN56384,REFSEQ:NP_001286589,UniProt/TrEMBL:Q8MRE7; MD5=65ba814167c8aeeda9d8b243c1c582c5; length=605; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 605 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAAKRRASS SNSSGSSNTS GSSNGNEQHS QQQHLQLQQQ QQQHAQPNEY QQLLQHPHHH  60
   61 YQQHYSGNNN TSGNNSNSSN TQQYHQRQQQ HQATLRDCSV KLPLDILWLP KSAMRPAGPD 120
  121 TSPTDCILVV GVSRPKLAVV FLTVMLISLF LTFHVLYDSA VYNIQAAQAV HERHRLSMTA 180
  181 SASALASSSS SSSNSGSSFS SAGGASNHLP VFVKPVPSSN QLSHPMVFPS SRVHFPKTSR 240
  241 RLPQALIIGV RKCGTRALLE MLYLHPRIQK AGGEVHFFDR DENYLKGLEW YRKKMPHSFR 300
  301 GQITIEKSPS YFVSPEVPER VRAMNASIKL LLIVREPVTR AISDYTQLRS HAATAILPLA 360
  361 EKDPPSPRES SGGGAGGGGA GGGGGSGTAA AKMPTQSLLY AKLQSARGYD NALLGGSGAG 420
  421 AKETKGKTVS SSLVRRQALG SGGGVAGAAM TTTTMSPMAS AAQMAAKSFE ELAIFPNGTV 480
  481 NEAYRPLSIS MYHVHLHRWL EVFPREQLLV VNGDRLIEDP VSQLKRIEAF LGIEHRVNSE 540
  541 HFYFNETKGF YCLRYDNGDR CLRETKGRKH PHVDPVVVSR LRKFFAEYNQ RFYELVGEDL 600
  601 GWPEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] MSA 2.041965 View MSA. No confident structure predictions are available.
    2 View Details [161..415] PSI-BLAST 36.69897 Heparan sulfate N-deacetylase/N-sulfotransferase domain
    3 View Details [416..605] PSI-BLAST 50.69897 Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.470983068319171 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0582794297634999 bayes_pls_golite062009
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.470983068319171 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0582794297634999 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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