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View Structure Prediction Details

Protein: FBpp0311723, Hs3...
Organism: Drosophila melanogaster
Length: 605 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311723, Hs3....

Description E-value Query
Range
Subject
Range
gi|58388364, gi|... - gi|58388364|ref|XP_316229.2| ENSANGP00000017049 [Anopheles gambiae str. PEST], gi|55238982|gb|EAA114...
342.0 [0..95] [605..1]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAAKRRASS SNSSGSSNTS GSSNGNEQHS QQQHLQLQQQ QQQHAQPNEY QQLLQHPHHH  60
   61 YQQHYSGNNN TSGNNSNSSN TQQYHQRQQQ HQATLRDCSV KLPLDILWLP KSAMRPAGPD 120
  121 TSPTDCILVV GVSRPKLAVV FLTVMLISLF LTFHVLYDSA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VYNIQAAQAV HERHRLSMTA SASALASSSS SSSNSGSSFS SAGGASNHLP VFVKPVPSSN  60
   61 QLSHPMVFPS SRVHFPKTSR RLPQALIIGV RKCGTRALLE MLYLHPRIQK AGGEVHFFDR 120
  121 DENYLKGLEW YRKKMPHSFR GQITIEKSPS YFVSPEVPER VRAMNASIKL LLIVREPVTR 180
  181 AISDYTQLRS HAATAILPLA EKDPPSPRES SGGGAGGGGA GGGGGSGTAA AKMPTQSLLY 240
  241 AKLQSARGYD NALLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.69897
Match: 1nstA
Description: Heparan sulfate N-deacetylase/N-sulfotransferase domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.470983068319171 bayes_pls_golite062009
hydrolase activity 0.0582794297634999 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [416-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSGAGAKETK GKTVSSSLVR RQALGSGGGV AGAAMTTTTM SPMASAAQMA AKSFEELAIF  60
   61 PNGTVNEAYR PLSISMYHVH LHRWLEVFPR EQLLVVNGDR LIEDPVSQLK RIEAFLGIEH 120
  121 RVNSEHFYFN ETKGFYCLRY DNGDRCLRET KGRKHPHVDP VVVSRLRKFF AEYNQRFYEL 180
  181 VGEDLGWPEE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.69897
Match: 1t8uA
Description: Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.470983068319171 bayes_pls_golite062009
hydrolase activity 0.0582794297634999 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle