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Protein Overview: FBpp0293405

General Information:
Name(s) found: FBpp0293405 [FlyBase]
Description(s) found:
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  • gi|24655079|ref|NP_611340.1| CG5226 [Drosophila melanogaster] [NCBI NR]
  • gi|21627025|gb|AAF57678.2| CG5226 [Drosophila melanogaster] [NCBI NR]
  • gi|201065585|gb|ACH92202.1| FI03236p [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=2R:join(14406687..14406957,14407933..14408165,14408223..14408800,14409152..14409293,14409361..14409722,14409786..14409948,14410022..14410225,14410478..14410546,14410699..14410704); ID=FBpp0293405; name=CG43066-PA; parent=FBgn0262476,FBtr0304865; dbxref=REFSEQ:NP_611340,GB_protein:AAF57678,FlyBase:FBpp0293405,FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,FlyBase_Annotation_IDs:CG43066-PA,FlyMine:FBpp0293405,modMine:FBpp0293405; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG5226 (CG5226, FBgn0034355). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14402081..14412922. It has the cytological map location 55D1. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity; transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: neurotransmitter transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG5226-PA translation from_gene[CG5226 CG5226 FBgn0034355] seq_release:3 mol_weight=75107 cds_boundaries:(2R:13,582,902..13,586,916[+]) aa_length:675 transcript_info:[CG5226-RA seq_release:3] gene_info:[gene symbol:CG5226 FBgn0034355 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V8I8) CG5226 protein [DrosMelano7227.FASTAC.txt]
  • CG5226-PA [Drosophila melanogaster]gi|24655079|ref|NP_611340.1| CG5226-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(14406687..14406957,14407933..14408165,14408223..14408800,14409152..14409293,14409361..14409722,14409786..14409948,14410022..14410225,14410478..14410546,14410699..14410704); ID=FBpp0085877; name=CG5226-PA; parent=FBgn0034355,FBtr0 [fly-100309-contam.fasta]
  • CG5226-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(14406687..14406957,14407933..14408165,14408223..14408800,14409152..14409293,14409361..14409722,14409786..14409948,14410022..14410225,14410478..14410546,14410699..14410704); ID=FBpp0085877; name=CG5226-PA; parent=FBgn0034355,FBtr0086698; dbxref=FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,GB_protein:AAF57678.2,REFSEQ:NP_611340,GB_protein:AAF57678; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(14406687..14406957,14407933..14408165,14408223..14408800,14409152..14409293,14409361..14409722,14409786..14409948,14410022..14410225,14410478..14410546,14410699..14410704); ID=FBpp0085877; name=CG5226-PA; parent=FBgn0034355,FBtr0086698; dbxref=FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,GB_protein:AAF57678.2,REFSEQ:NP_611340,GB_protein:AAF57678; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Transporter OS=Drosophila melanogaster GN=CG5226-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(14406687..14406957,14407933..14408165,14408223..14408800,14409152..14409293,14409361..14409722,14409786..14409948,14410022..14410225,14410478..14410546,14410699..14410704); ID=FBpp0293405; name=CG43066-PA; parent=FBgn0262476,FBtr0304865; dbxref=REFSEQ:NP_611340,GB_protein:AAF57678,FlyBase:FBpp0293405,FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,FlyBase_Annotation_IDs:CG43066-PA,FlyMine:FBpp0293405,modMine:FBpp0293405; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(18519182..18519452,18520428..18520660,18520718..18521295,18521647..18521788,18521856..18522217,18522281..18522443,18522517..18522720,18522973..18523041,18523194..18523199); ID=FBpp0293405; name=CG43066-PA; parent=FBgn0262476,FBtr0304865; dbxref=REFSEQ:NP_611340,GB_protein:AAF57678,FlyBase:FBpp0293405,FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,FlyBase_Annotation_IDs:CG43066-PA,FlyMine:FBpp0293405,modMine:FBpp0293405; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(18519182..18519452,18520428..18520660,18520718..18521295,18521647..18521788,18521856..18522217,18522281..18522443,18522517..18522720,18522973..18523041,18523194..18523199); ID=FBpp0293405; name=CG43066-PA; parent=FBgn0262476,FBtr0304865; dbxref=REFSEQ:NP_611340,GB_protein:AAF57678,FlyBase:FBpp0293405,FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,FlyBase_Annotation_IDs:CG43066-PA,FlyMine:FBpp0293405,modMine:FBpp0293405; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A0A0B4K7V4, Transporter OS=Drosophila melanogaster GN=CG5226-RA PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0293405 type=protein; loc=2R:join(18519182..18519452,18520428..18520660,18520718..18521295,18521647..18521788,18521856..18522217,18522281..18522443,18522517..18522720,18522973..18523041,18523194..18523199); ID=FBpp0293405; name=CG43066-PA; parent=FBgn0262476,FBtr0304865; dbxref=REFSEQ:NP_611340,GB_protein:AAF57678,FlyBase:FBpp0293405,FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,FlyBase_Annotation_IDs:CG43066-PA,FlyMine:FBpp0293405,modMine:FBpp0293405; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(18519182..18519452,18520428..18520660,18520718..18521295,18521647..18521788,18521856..18522217,18522281..18522443,18522517..18522720,18522973..18523041,18523194..18523199); ID=FBpp0293405; name=CG43066-PA; parent=FBgn0262476,FBtr0304865; dbxref=REFSEQ:NP_611340,GB_protein:AAF57678,FlyBase:FBpp0293405,FlyBase:FBpp0085877,FlyBase_Annotation_IDs:CG5226-PA,FlyBase_Annotation_IDs:CG43066-PA,UniProt/TrEMBL:A1ZB95,FlyMine:FBpp0293405,modMine:FBpp0293405; MD5=bb1f66dec8c0bb96e8def1fae1897793; length=675; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 675 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IEA]
    Biological Process: neurotransmitter transport [ISS]
    Molecular Function: neurotransmitter transporter activity [ISS]
    neurotransmitter:sodium symporter activity [IEA]
    transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATKIIDAP RNGHEMAPLN TRARGDGTHG VTIVLTAPQR NSVQSVDIPG NEPERAAWSG  60
   61 KMQFFLSIIG YSVGLGNIWR FPYLCQQNGG GAFLIPFMVM LILEGIPLFL IELGIGQRMR 120
  121 LGALGVWNTI HPWLGGIGIS SCIVTLFVAL YYNVIITWVF FYLFNSFRYP LPWSSCPLNG 180
  181 TGFELEECAK SSETTYFWYR TTLDAAPSMD EPGGLKWWIV LCLMLSWTIV FFIVMKGIQS 240
  241 SGKVVYFTSL FPYIVLTIFF IRGITLRGAG AGLMHMYTPK VEKLLEPTVW LDAATQVFYS 300
  301 FGLAFGSLIA FGSYNTPKNN CVRDVLLVSV CNAVTAIYAS VVIFAILGFK ATVNVDRCVA 360
  361 SNTEILVKNK LLGLNDTQGY EQAMSLLNGT ELLRLQLSEC SLAHELDNAA EGTGLAFIVF 420
  421 TQAIVELPGA PFWAVLFFTM LLSLGLGSQI GILEGMLCTL FDIDIIKRVK KQHVTGVVCL 480
  481 FCFIVGFIFC TGAGEYWLKM FDSFAGTIGL VVVALMEMIA VIFIYGHERF TEDIFQMTGY 540
  541 RPGRYWQWTW RYIGPVIMVC ILVSSVVFMV IRNPTYGAWN ADLGMIEQKS YPNWVMGIAL 600
  601 SMILAGVLPM PIVFLMRSFQ CLKVDLDIHQ GSIRRNETTA STKEMIDNDD DNMSPDMPPQ 660
  661 DSLAATRFTI GDFEN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..571] PSI-BLAST 61.39794 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
    2 View Details [572..675] MSA 4.298995 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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