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Protein Overview: olf186-F-PA, olf...

General Information:
Name(s) found: FBpp0307679 [FlyBase]
olf186-F-PA / FBpp0085976 [FlyBase]
olf186-F-PB / FBpp0085974 [FlyBase]
Description(s) found:
Found 45 descriptions.
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  • type=protein; loc=2R:join(13738603..13738965,13745147..13745302,13746763..13747299); ID=FBpp0307679; name=olf186-F-PF; parent=FBgn0041585,FBtr0336698; dbxref=FlyBase:FBpp0307679,FlyBase_Annotation_IDs:CG11430-PF,REFSEQ:NP_995881,GB_protein:AAS64814; MD5=7b06bb5463196e4c7eeab496197b2381; length=351; release=r5.56; species=Dmel; [FlyBase]
  • The gene olf186-F is referred to in FlyBase by the symbol Dmel\olf186-F (CG11430, FBgn0041585). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13730950..13748075. It has the cytological map location 54F1-54F3. There is experimental evidence that it has the molecular function</span>: store-operated calcium channel activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of calcium ion transport via store-operated calcium channel activity; regulation of calcium ion transport via store-operated calcium channel activity; nervous system development; positive regulation of calcium ion transport; positive regulation of NFAT protein import into nucleus; store-operated calcium entry. 27 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene olf186-F is referred to in FlyBase by the symbol Dmel\olf186-F (CG11430, FBgn0041585). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13730950..13748075. It has the cytological map location 54F1-54F3. There is experimental evidence that it has the molecular function</span>: store-operated calcium channel activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of calcium ion transport via store-operated calcium channel activity; regulation of calcium ion transport via store-operated calcium channel activity; nervous system development; positive regulation of calcium ion transport; positive regulation of NFAT protein import into nucleus; store-operated calcium entry. 27 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 351 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [NAS]
    Biological Process: positive regulation of NFAT protein import into nucleus [IMP]
    store-operated calcium entry [IMP]
    positive regulation of calcium ion transport [IMP]
    regulation of calcium ion transport via store-operated calcium channel activity [IMP]
    nervous system development [IMP]
    positive regulation of calcium ion transport via store-operated calcium channel activity [IMP]
    Molecular Function: store-operated calcium channel activity [IMP]
    [NOT]serine-type endopeptidase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVWTTANNS GLETPTKSPI TSSVPRAARS SAVITTGNHQ QHHFQHVVAA AVAAATSVAT  60
   61 GHQFQQQFPL HAHPHPQHHS NSPTGSGSNS NNSAGFQRTS ISNSLLQFPP PPPPSSQNQA 120
  121 KPRGHHRTAS SSMSQSGEDL HSPTYLSWRK LQLSRAKLKA SSKTSALLSG FAMVAMVEVQ 180
  181 LDHDTNVPPG MLIAFAICTT LLVAVHMLAL MISTCILPNI ETVCNLHSIS LVHESPHERL 240
  241 HWYIETAWAF STLLGLILFL LEIAILCWVK FYDLSPPAAW SACVVLIPVM IIFMAFAIHF 300
  301 YRSLVSHKYE VTVSGIRELE MLKEQMEQDH LEHHNNIRNN GMNYGASGDI V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] MSA 1.015961 View MSA. No confident structure predictions are available.
    2 View Details [124..351] MSA 2.018933 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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